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This study aims to explore the application of Operations Research (OR) techniques for optimizing job assignment processes using MATLAB software. Job assignment is a critical task in many organizations, and efficient allocation of tasks to individuals or resources can significantly improve productivity and overall performance. By leveraging OR methodologies and MATLAB's computational capabilities, this study seeks to develop an optimized job assignment model that minimizes costs, maximizes resource utilization, and enhances operational efficiency. The book begins with a comprehensive literature review of existing research on job assignment and OR techniques, including linear programming, integer programming, and assignment problems. Various models and algorithms will be studied, focusing on their suitability for job assignment optimization.