Layered structures, when supporting the Maxwell Wagner polarization mechanism, exhibit very large effective electric permittivity and thus can be used for miniaturizing purposes. However, the large interfacial dimensions evolved, limit the Maxwell Wagner polarization at relatively low frequencies. This book is a study on the waveguiding properties of laminar substrates consisting of metal-insulator-semiconductor (MIS) layers. The propagation characteristics of MIS lines are controlled by the resistivity of the substrate, the operating frequency and the ratio of the semiconductor to insulator layer thicknesses. Additionally, it is demonstrated how intentionally planted polarization states can be used for further exploiting the Maxwell Wagner polarization mechanism. Finally, potential applications of this method, such as delay lines, distributed low-pass filters, and couplers are presented.