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The primary objective of present work is to explore the simple, fast, efficient, cost effective, environmentally friendly and non-toxic methodology for the preparation of different types of inorganic and organic nanoparticles and to develop an effective carrier that would be suitable for gene delivery in plants and other therapeutic applications. In the present study, we have developed different types of nanoparticles (a) Ceramic nanoparticles for gene delivery (i.e. calcium phosphate) and superparamagnetic iron oxide nanoparticles to check its potential cytotoxicity for further successful…mehr

Produktbeschreibung
The primary objective of present work is to explore the simple, fast, efficient, cost effective, environmentally friendly and non-toxic methodology for the preparation of different types of inorganic and organic nanoparticles and to develop an effective carrier that would be suitable for gene delivery in plants and other therapeutic applications. In the present study, we have developed different types of nanoparticles (a) Ceramic nanoparticles for gene delivery (i.e. calcium phosphate) and superparamagnetic iron oxide nanoparticles to check its potential cytotoxicity for further successful biomedical applications. (b) Metal nanoparticles i.e. gold and silver nanoparticles were prepared via simple and eco friendly method. Scientists, currently employing different non-viral vectors such as liposomes, polymer, nanoparticles etc. as gene delivery agents in mammalian cells and few are reported with plant cells. In plant, Agrobacterium mediated method, gene gun, lipofection and biolistics are the common conventional methods for gene delivery have been reported but, they possess several limitations.
Autorenporträt
Dr. M. Samim is currently a faculty of Chemistry at Hamdard University. Area of work includes drug delivery, gene delivery, synthesis of metal nanoparticles, Biomaterials nanotoxicology and Nanomedicine. He has published 45 articles in journals of high impact factor and filed six National patents and two international patents on Nano formulation.