This book is about bone healing an tissue engineering in rat model. It is useful for pathology and orthopedics student.Bone grafting is performed to restore bone that has been lost due to trauma, tumors, osteomyelitis etc... that require replacement. Bone grafts are necessary to provide support, fill voids, and enhance biologic repair of skeletal defects. Different bone grafts have been used in bone healing using. Biologic bone grafts can be divided into the following subtypes: autografts, allografts, xenografts, synthetic materials, and any combination thereof. Bone grafts can be employed for functions other than to stimulate bone formation within a defect. The graft laid over facial bone surfaces could augment the insolent prominence or restore facial contour. Xenografts are grafts shared between different species. There are several studys about using different animals in xenografting such as canine cattle, porcine and coral graft. The medical literature regarding xenograft, which is solely osteoconductive, is incongruous. We used cattle, poultry, tortoise; fish bone as xenografts in this study.