Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms

Herausgeber: Felton, Linda A.

• Broschiertes Buch

Produktbeschreibung

Aqueous-based film coating has become routine in the pharmaceutical industry. This process eliminates the use of organic solvents and thus avoids economic, environmental, and toxicological issues related to residual solvents and solvent recovery. Aqueous-based coating, however, is complex and many variables may impact the final product and its performance. This fourth edition of Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms aims to provide insight into the factors and parameters that should be considered and controlled for the successful development and commercialization of a coated product. The fourth edition has been revised and expanded to reflect the most recent scientific advancements from the literature. The contributing authors explain in detail, using illustrated examples, appropriate steps to solve and ideally avoid formulation, processing, and stability problems and to achieve an optimized dosage form. Trade names and chemical names of commercially marketed coatings are used throughout the text to help familiarize the reader with the various materials available for pharmaceutical applications. This book will be a valuable resource for anyone in the pharmaceutical industry working in the area of aqueous-based film coating.

---

Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.

Produktdetails

• Verlag: CRC Press
• 4. Auflage
• Seitenzahl: 416
• Erscheinungstermin: 18. Dezember 2020
• Englisch
• Abmessung: 254mm x 178mm x 22mm
• Gewicht: 779g
• ISBN-13: 9780367736873
• ISBN-10: 036773687X
• Artikelnr.: 69890944

Autorenporträt

Linda A. Felton, Ph.D. is a Professor of Pharmaceutics and Chair of the Department of Pharmaceutical Sciences in the College of Pharmacy at the University of New Mexico. She earned a B.S. in Pharmacy and a Ph.D. in Pharmaceutics from the University of Texas at Austin. Her research interests are focused on polymeric film coating and modified release drug delivery systems. She has presented her work at national and international conferences and has published extensively in peer-reviewed journals. Dr. Felton is a reviewer for a number of pharmaceutical journals and an editorial board member of Drug Development and Industrial Pharmacy. She is the Manufacturing Section Editor of the 22nd edition of "Remington: The Science and Practice of Pharmacy", the Co-Editor of the 3rd edition of "Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms", and Editor of 'Remington: Essentials of Pharmaceutics". Dr. Felton has a joint appointment with the Department of Veteran's Affairs Cooperative Studies Program where she oversees the formulation development of clinical trials materials. She is a current member of the American Association of Pharmaceutical Scientists, the Controlled Release Society, and the International Society for Pharmaceutical Engineering

Inhaltsangabe

Aqueous-based polymeric coating. Pseudolatex dispersions for controlled
drug delivery. Processing and equipment considerations for aqueous-based
coatings. Mechanical properties of polymeric films prepared from aqueous
dispersions. Defects in aqueous film coated solid oral dosage form.
Adhesion of polymeric films. Influence of insoluble additives on the
properties of polymeric coating systems. Process and formulation factors
affecting drug release from pellets coated with ethylcellulose pseudolatex
Aquacoat. Chemistry and application properties of polymethacrylate systems.
Application of HPMC and HPMCAS to aqueous film coating of pharmaceutical
dosage forms. The applications of formulated systems for aqueous film
coating of pharmaceutical solid oral dosage forms. *Substrate
considerations when developing an aqueous film coated solid oral dosage
form. Polymer interactions with drugs and excipients. Physical aging of
polymers and it effect on the stability of solid oral dosage forms.