Alan J McComas
Aranzio's Seahorse and the Search for Memory and Consciousness
Alan J McComas
Aranzio's Seahorse and the Search for Memory and Consciousness
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Alan J. McComas recounts the research that led to recognition of the hippocampus, a structure deep within the brain, as being primarily responsible for memory. This intriguing and exciting account includes observations on patients with memory loss as well as insights from ingenious laboratory experiments.
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Alan J. McComas recounts the research that led to recognition of the hippocampus, a structure deep within the brain, as being primarily responsible for memory. This intriguing and exciting account includes observations on patients with memory loss as well as insights from ingenious laboratory experiments.
Produktdetails
- Produktdetails
- Verlag: Oxford University Press, USA
- Seitenzahl: 352
- Erscheinungstermin: 30. Dezember 2022
- Englisch
- Abmessung: 241mm x 180mm x 36mm
- Gewicht: 862g
- ISBN-13: 9780192868244
- ISBN-10: 0192868241
- Artikelnr.: 66706857
- Verlag: Oxford University Press, USA
- Seitenzahl: 352
- Erscheinungstermin: 30. Dezember 2022
- Englisch
- Abmessung: 241mm x 180mm x 36mm
- Gewicht: 862g
- ISBN-13: 9780192868244
- ISBN-10: 0192868241
- Artikelnr.: 66706857
Born in Western Australia, Alan J. McComas received his medical and neurological training in Newcastle upon Tyne (UK), with postdoctoral studies at University College London and the National Hospital for Nervous Diseases, Queen Square, London. He was later appointed Head of Neurology and then of Biomedical Sciences at McMaster University, Canada. Initially specializing in neuromuscular disorders, McComas is best known for having pioneered a method for estimating numbers of motor nerve cells (motoneurons) in the spinal cords and brain stems of living human subjects. Later interests included reflex mechanisms and muscle fatigue, and he (with colleague Adrian Upton) pioneered the use of transcranial magnetic stimulation for the treatment of migraine. As a medical historian, McComas wrote the award-winning Galvani's Spark. The Story of the Nerve Impulse. He is now Emeritus Professor of Medicine (Neurology) at McMaster University.
* Part I: Memory
* 1: The undisturbed seahorse. (Europe, 16th-20th centuries).
* 2: A portentous crossing. (Montreal, 1944-1948: Donald Hebb, Peter
and Brenda Milner).
* 3: Graduate studies at MNI. (Montreal, 1948-1954: Peter and Brenda
Milner, James Olds, Wilder Penfield, Herbert Jasper).
* 4: Bold surgeon and compliant patient. (Hartford (Connecticut), 1953:
William Scoville, Brenda Milner, Henry Molaison).
* 5: Triumph and an unprovoked attack. (Montreal, London, 1957; Wilder
Penfield, Francis Walshe).
* 6: The path to psychiatry. (New York, 1957: Eric Kandel).
* 7: A trip to Australia. (Oslo, Canberra, 1961: Per Andersen, John
Eccles).
* 8: Taking stock. (Montreal, 1960: Brenda Milner).
* 9: Visual focus. (Cambridge (Massachusetts), 1962, Stephen Kuffler,
David Hubel, Torsten Wiesel).
* 10: Enter the giant sea slug. (Paris, 1962: Eric Kandel, Ladislav
Tauc).
* 11: Human neurons--success and disappointment. (Paris, Uppsala,
1960s: Denise Albe-Fessard, Karl-Erik Hagbarth).
* 12: Human neurons--success and disappointment. (Paris, Uppsala,
1960s: Denise Albe-Fessard, Karl-Erik Hagbarth).
* 13: Return of the slug. (New York, 1965: Eric Kandel).
* 14: Polish insights. (Warsaw, 1968: Jerzy Konorski).
* 15: Continuing excitation in Norway. (Oslo, 1968: Terje Lømo, Timothy
Bliss).
* 16: Revelation on Gower Street. (London, 1971: Patrick Wall, John
O'Keefe).
* 17: Mathematics and the hippocampus. (Cambridge (UK), 1971: David
Marr).
* 18: 1980: departures.
* 19: Hidden faces. (Oxford, New York: Edmund Rolls, Eric Kandel).
* 20: More than a headache. (London, 1985: Clive and Deborah Wearing).
* 21: Unexpectedly, a grid. (London, Oslo, 1996: Edvard and May-Britt
Moser).
* 22: A telephone call. (Stockholm, New York, Cambridge
(Massachusetts), 2000: Eric Kandel).
* 23: Death and disorder. (Bickford (Connecticut), San Diego, 2008:
Henry Molaison, Suzanne Corkin, Jacopo Annese).
* 24: Jennifer Aniston discovered. (Los Angeles, 2005. Itzhak Fried,
Christof Koch, Rodrigo Quian Quiroga).
* 25: New cells or not? (1983--present, New York, Boston, Princeton,
New Haven, La Jolla: Fernando Nottebohn, Joseph Altman, Michael
Kaplan, Elizabeth Gould, Pasko Rakic, Fred Gage).
* 26: Neurons that glow. (Toronto, Cambridge (Massachusetts), 2020:
Sheena Josselyn, Susuma Tonegawa).
* 27: Summary.
* Part II: The Evolution of Consciousness
* 28: Preamble.
* 29: Definition of consciousness.
* 30: Theories of consciousness.
* 31: Recognition of limbic system within brain.
* 32: Recognition of limbic system within brain.
* 33: Clinical evidence of hippocampal (limbic) involvement in
consciousness
* 34: Animal evidence consistent with consciousness generation in
limbic system (rather than cortex).
* 35: Animal evidence consistent with consciousness generation in
limbic system (rather than cortex).
* 36: The evolutionary argument.
* 37: The minimum time argument.
* 38: Clive Wearing and Henry Molaison reconsidered.
* 39: Role of the amygdala.
* 40: Role of the non-hippocampal cortex.
* 41: Back to the hippocampus.
* 42: The numbers game
* 43: Speculations on spatial maps and other issues.
* 44: Final note: the multi-tasking hippocampus.
* 45: Recapitulation and synthesis
* 46: Epilogue
* 1: The undisturbed seahorse. (Europe, 16th-20th centuries).
* 2: A portentous crossing. (Montreal, 1944-1948: Donald Hebb, Peter
and Brenda Milner).
* 3: Graduate studies at MNI. (Montreal, 1948-1954: Peter and Brenda
Milner, James Olds, Wilder Penfield, Herbert Jasper).
* 4: Bold surgeon and compliant patient. (Hartford (Connecticut), 1953:
William Scoville, Brenda Milner, Henry Molaison).
* 5: Triumph and an unprovoked attack. (Montreal, London, 1957; Wilder
Penfield, Francis Walshe).
* 6: The path to psychiatry. (New York, 1957: Eric Kandel).
* 7: A trip to Australia. (Oslo, Canberra, 1961: Per Andersen, John
Eccles).
* 8: Taking stock. (Montreal, 1960: Brenda Milner).
* 9: Visual focus. (Cambridge (Massachusetts), 1962, Stephen Kuffler,
David Hubel, Torsten Wiesel).
* 10: Enter the giant sea slug. (Paris, 1962: Eric Kandel, Ladislav
Tauc).
* 11: Human neurons--success and disappointment. (Paris, Uppsala,
1960s: Denise Albe-Fessard, Karl-Erik Hagbarth).
* 12: Human neurons--success and disappointment. (Paris, Uppsala,
1960s: Denise Albe-Fessard, Karl-Erik Hagbarth).
* 13: Return of the slug. (New York, 1965: Eric Kandel).
* 14: Polish insights. (Warsaw, 1968: Jerzy Konorski).
* 15: Continuing excitation in Norway. (Oslo, 1968: Terje Lømo, Timothy
Bliss).
* 16: Revelation on Gower Street. (London, 1971: Patrick Wall, John
O'Keefe).
* 17: Mathematics and the hippocampus. (Cambridge (UK), 1971: David
Marr).
* 18: 1980: departures.
* 19: Hidden faces. (Oxford, New York: Edmund Rolls, Eric Kandel).
* 20: More than a headache. (London, 1985: Clive and Deborah Wearing).
* 21: Unexpectedly, a grid. (London, Oslo, 1996: Edvard and May-Britt
Moser).
* 22: A telephone call. (Stockholm, New York, Cambridge
(Massachusetts), 2000: Eric Kandel).
* 23: Death and disorder. (Bickford (Connecticut), San Diego, 2008:
Henry Molaison, Suzanne Corkin, Jacopo Annese).
* 24: Jennifer Aniston discovered. (Los Angeles, 2005. Itzhak Fried,
Christof Koch, Rodrigo Quian Quiroga).
* 25: New cells or not? (1983--present, New York, Boston, Princeton,
New Haven, La Jolla: Fernando Nottebohn, Joseph Altman, Michael
Kaplan, Elizabeth Gould, Pasko Rakic, Fred Gage).
* 26: Neurons that glow. (Toronto, Cambridge (Massachusetts), 2020:
Sheena Josselyn, Susuma Tonegawa).
* 27: Summary.
* Part II: The Evolution of Consciousness
* 28: Preamble.
* 29: Definition of consciousness.
* 30: Theories of consciousness.
* 31: Recognition of limbic system within brain.
* 32: Recognition of limbic system within brain.
* 33: Clinical evidence of hippocampal (limbic) involvement in
consciousness
* 34: Animal evidence consistent with consciousness generation in
limbic system (rather than cortex).
* 35: Animal evidence consistent with consciousness generation in
limbic system (rather than cortex).
* 36: The evolutionary argument.
* 37: The minimum time argument.
* 38: Clive Wearing and Henry Molaison reconsidered.
* 39: Role of the amygdala.
* 40: Role of the non-hippocampal cortex.
* 41: Back to the hippocampus.
* 42: The numbers game
* 43: Speculations on spatial maps and other issues.
* 44: Final note: the multi-tasking hippocampus.
* 45: Recapitulation and synthesis
* 46: Epilogue
* Part I: Memory
* 1: The undisturbed seahorse. (Europe, 16th-20th centuries).
* 2: A portentous crossing. (Montreal, 1944-1948: Donald Hebb, Peter
and Brenda Milner).
* 3: Graduate studies at MNI. (Montreal, 1948-1954: Peter and Brenda
Milner, James Olds, Wilder Penfield, Herbert Jasper).
* 4: Bold surgeon and compliant patient. (Hartford (Connecticut), 1953:
William Scoville, Brenda Milner, Henry Molaison).
* 5: Triumph and an unprovoked attack. (Montreal, London, 1957; Wilder
Penfield, Francis Walshe).
* 6: The path to psychiatry. (New York, 1957: Eric Kandel).
* 7: A trip to Australia. (Oslo, Canberra, 1961: Per Andersen, John
Eccles).
* 8: Taking stock. (Montreal, 1960: Brenda Milner).
* 9: Visual focus. (Cambridge (Massachusetts), 1962, Stephen Kuffler,
David Hubel, Torsten Wiesel).
* 10: Enter the giant sea slug. (Paris, 1962: Eric Kandel, Ladislav
Tauc).
* 11: Human neurons--success and disappointment. (Paris, Uppsala,
1960s: Denise Albe-Fessard, Karl-Erik Hagbarth).
* 12: Human neurons--success and disappointment. (Paris, Uppsala,
1960s: Denise Albe-Fessard, Karl-Erik Hagbarth).
* 13: Return of the slug. (New York, 1965: Eric Kandel).
* 14: Polish insights. (Warsaw, 1968: Jerzy Konorski).
* 15: Continuing excitation in Norway. (Oslo, 1968: Terje Lømo, Timothy
Bliss).
* 16: Revelation on Gower Street. (London, 1971: Patrick Wall, John
O'Keefe).
* 17: Mathematics and the hippocampus. (Cambridge (UK), 1971: David
Marr).
* 18: 1980: departures.
* 19: Hidden faces. (Oxford, New York: Edmund Rolls, Eric Kandel).
* 20: More than a headache. (London, 1985: Clive and Deborah Wearing).
* 21: Unexpectedly, a grid. (London, Oslo, 1996: Edvard and May-Britt
Moser).
* 22: A telephone call. (Stockholm, New York, Cambridge
(Massachusetts), 2000: Eric Kandel).
* 23: Death and disorder. (Bickford (Connecticut), San Diego, 2008:
Henry Molaison, Suzanne Corkin, Jacopo Annese).
* 24: Jennifer Aniston discovered. (Los Angeles, 2005. Itzhak Fried,
Christof Koch, Rodrigo Quian Quiroga).
* 25: New cells or not? (1983--present, New York, Boston, Princeton,
New Haven, La Jolla: Fernando Nottebohn, Joseph Altman, Michael
Kaplan, Elizabeth Gould, Pasko Rakic, Fred Gage).
* 26: Neurons that glow. (Toronto, Cambridge (Massachusetts), 2020:
Sheena Josselyn, Susuma Tonegawa).
* 27: Summary.
* Part II: The Evolution of Consciousness
* 28: Preamble.
* 29: Definition of consciousness.
* 30: Theories of consciousness.
* 31: Recognition of limbic system within brain.
* 32: Recognition of limbic system within brain.
* 33: Clinical evidence of hippocampal (limbic) involvement in
consciousness
* 34: Animal evidence consistent with consciousness generation in
limbic system (rather than cortex).
* 35: Animal evidence consistent with consciousness generation in
limbic system (rather than cortex).
* 36: The evolutionary argument.
* 37: The minimum time argument.
* 38: Clive Wearing and Henry Molaison reconsidered.
* 39: Role of the amygdala.
* 40: Role of the non-hippocampal cortex.
* 41: Back to the hippocampus.
* 42: The numbers game
* 43: Speculations on spatial maps and other issues.
* 44: Final note: the multi-tasking hippocampus.
* 45: Recapitulation and synthesis
* 46: Epilogue
* 1: The undisturbed seahorse. (Europe, 16th-20th centuries).
* 2: A portentous crossing. (Montreal, 1944-1948: Donald Hebb, Peter
and Brenda Milner).
* 3: Graduate studies at MNI. (Montreal, 1948-1954: Peter and Brenda
Milner, James Olds, Wilder Penfield, Herbert Jasper).
* 4: Bold surgeon and compliant patient. (Hartford (Connecticut), 1953:
William Scoville, Brenda Milner, Henry Molaison).
* 5: Triumph and an unprovoked attack. (Montreal, London, 1957; Wilder
Penfield, Francis Walshe).
* 6: The path to psychiatry. (New York, 1957: Eric Kandel).
* 7: A trip to Australia. (Oslo, Canberra, 1961: Per Andersen, John
Eccles).
* 8: Taking stock. (Montreal, 1960: Brenda Milner).
* 9: Visual focus. (Cambridge (Massachusetts), 1962, Stephen Kuffler,
David Hubel, Torsten Wiesel).
* 10: Enter the giant sea slug. (Paris, 1962: Eric Kandel, Ladislav
Tauc).
* 11: Human neurons--success and disappointment. (Paris, Uppsala,
1960s: Denise Albe-Fessard, Karl-Erik Hagbarth).
* 12: Human neurons--success and disappointment. (Paris, Uppsala,
1960s: Denise Albe-Fessard, Karl-Erik Hagbarth).
* 13: Return of the slug. (New York, 1965: Eric Kandel).
* 14: Polish insights. (Warsaw, 1968: Jerzy Konorski).
* 15: Continuing excitation in Norway. (Oslo, 1968: Terje Lømo, Timothy
Bliss).
* 16: Revelation on Gower Street. (London, 1971: Patrick Wall, John
O'Keefe).
* 17: Mathematics and the hippocampus. (Cambridge (UK), 1971: David
Marr).
* 18: 1980: departures.
* 19: Hidden faces. (Oxford, New York: Edmund Rolls, Eric Kandel).
* 20: More than a headache. (London, 1985: Clive and Deborah Wearing).
* 21: Unexpectedly, a grid. (London, Oslo, 1996: Edvard and May-Britt
Moser).
* 22: A telephone call. (Stockholm, New York, Cambridge
(Massachusetts), 2000: Eric Kandel).
* 23: Death and disorder. (Bickford (Connecticut), San Diego, 2008:
Henry Molaison, Suzanne Corkin, Jacopo Annese).
* 24: Jennifer Aniston discovered. (Los Angeles, 2005. Itzhak Fried,
Christof Koch, Rodrigo Quian Quiroga).
* 25: New cells or not? (1983--present, New York, Boston, Princeton,
New Haven, La Jolla: Fernando Nottebohn, Joseph Altman, Michael
Kaplan, Elizabeth Gould, Pasko Rakic, Fred Gage).
* 26: Neurons that glow. (Toronto, Cambridge (Massachusetts), 2020:
Sheena Josselyn, Susuma Tonegawa).
* 27: Summary.
* Part II: The Evolution of Consciousness
* 28: Preamble.
* 29: Definition of consciousness.
* 30: Theories of consciousness.
* 31: Recognition of limbic system within brain.
* 32: Recognition of limbic system within brain.
* 33: Clinical evidence of hippocampal (limbic) involvement in
consciousness
* 34: Animal evidence consistent with consciousness generation in
limbic system (rather than cortex).
* 35: Animal evidence consistent with consciousness generation in
limbic system (rather than cortex).
* 36: The evolutionary argument.
* 37: The minimum time argument.
* 38: Clive Wearing and Henry Molaison reconsidered.
* 39: Role of the amygdala.
* 40: Role of the non-hippocampal cortex.
* 41: Back to the hippocampus.
* 42: The numbers game
* 43: Speculations on spatial maps and other issues.
* 44: Final note: the multi-tasking hippocampus.
* 45: Recapitulation and synthesis
* 46: Epilogue