Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It…mehr
Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology. Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Professor Li graduated from Guangdong College of Traditional Chinese Medicine in 1955. He has more than 50-years experiences on Qinghaosu (artemisinin). He is the first to prove artemisinin's curative effect on falciparum malaria and severe malaria, and contribute in qinghaosu (artemisinin) research in Project 523. He devised and researched a series of artemisinin-based combinations: dihydroartemisinin-piperaquine phosphate-primaquine combination (CV8) which was registered and produced in Vienam in 1997. It was the first-line treatment drug for malaria and given for free in Vietnam. Dihydroartemisinin-piperaquine phosphate combination, Artemisinin- piperaquine combination both have been registered and produced in China. Dihydroartemisinin-piperaquine combination was included in the 2nd edition of "Malaria treatment Guidelines? by WHO in 2010. He has published over 50 papers on malaria research and artemisinin derivatives.
Inhaltsangabe
1. Discovery of Artemisinin and History of Research and Discovery of Artemisinin Antimalarials2. Biological Research of Artemisia annua L 3. Chemical Research on Artemisinin4. Artemisinin Derivatives and Analogues5. Pharmacological Study on Artemisinin and Its Derivatives6. Clinical Studies of Artemisinin and its Derivatives7. Artemether and Lumefantrine Combination 8. Artemisinin and Naphthoquine Phosphate Combination9. The Combination of Artemisinin Drugs and Pyronaridine10. Artemisinins and piperaquine phosphate combinations
1. Discovery of Artemisinin and History of Research and Discovery of Artemisinin Antimalarials2. Biological Research of Artemisia annua L 3. Chemical Research on Artemisinin4. Artemisinin Derivatives and Analogues5. Pharmacological Study on Artemisinin and Its Derivatives6. Clinical Studies of Artemisinin and its Derivatives7. Artemether and Lumefantrine Combination 8. Artemisinin and Naphthoquine Phosphate Combination9. The Combination of Artemisinin Drugs and Pyronaridine10. Artemisinins and piperaquine phosphate combinations
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