Artificial Cellulosome - Krauss, Jan
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Clostridium thermocellum achieves efficient cellulose degradation using multiprotein extracellular enzymatic complexes, termed cellulosomes. In this study an artificial cellulosome based on the modular structure of the Clostridium-cellulosome was developed which exhibits at least the degradation level of the native cellulosome. In this systme, hydrolytic cellulases from a C. thermocellum mutant are bound to the surface of nanoparticles. Thus, a highly active renewable system could be developed, that is able to compete with the commercially available cellulase preparations.

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Produktbeschreibung
Clostridium thermocellum achieves efficient cellulose degradation using multiprotein extracellular enzymatic complexes, termed cellulosomes. In this study an artificial cellulosome based on the modular structure of the Clostridium-cellulosome was developed which exhibits at least the degradation level of the native cellulosome. In this systme, hydrolytic cellulases from a C. thermocellum mutant are bound to the surface of nanoparticles. Thus, a highly active renewable system could be developed, that is able to compete with the commercially available cellulase preparations.
Autorenporträt
Born 14.10.1979 in Wertheim, Germany. 2000 - 2005 Study of Biology at the Maximilians-University Wuerzburg. 2006 Diploma thesis at the Max-Planck-Institute od Biophysics, Frankfurt/Main. 2007 - 2010 Dissertation at the Institute of Microbiology Technical University Munich.