Clinical practice experiences are critically important to determine that graduate students are expected to achieve the maximum level of clinical competence after receiving necessary and adequate theoretical and practical instructions. However the results of previous study suggested that most new bachelor graduates have adequate theoretical knowledge but lack competence in the clinical environment. Thus, this study is designed to assess factors affecting clinical practice competence of undergraduate health science student, Hawassa University, South, Ethiopia, 2015. This book was written to help researchers to develop the educational curriculum in the area of Medicine and Health Science. Its goal is to assess factors affecting clinical practice competency of undegraduate Health Science student.