Karakalpak Ustyurt, characterized by its peculiar geological and tectonic structure, geomorphology, the presence of very deep and drainless depressions, as well as diverse fauna, has attracted the attention of researchers since ancient times. Meanwhile, the data on geological, hydrogeological, geomorphological, soil and climatic conditions of the studied territory were obtained much later. Initial data on physical-geographical conditions and geological structure of the area were fragmentary and had a route-reconnaissance character. Nowadays outdated information about the Ustyurt Plateau has only historical significance. As it is known from historical data, the first land description of the Ustyurt Plateau territory was made in the second century by Claudius Ptolemy. And information about underground waters of the plateau was obtained much later. Until now we are still conducting research on the movement of underground waters and placement of minerals in the Ustyurt plain of the Republic of Karakalpakstan.