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The epidemic of atherosclerosis is recognized by the World Health Organization as a global threat, and is considered a potent independent risk factor for a cardiac event and a coronary heart disease equivalent. To determine the effectiveness of an educational program on atherosclerosis risk factors in patients at the Physician's Office, a quasi-experimental intervention study was conducted with 35 patients between the ages of 30 and 70 years dispensed at risk for atherosclerosis. Based on the needs identified, an educational program was designed and implemented. The proposal implemented had a favorable impact on the patients, since positive modifications were made in their lifestyles.