Clifford Smith, Alfred Jarecki

Atlas of Comparative Diagnostic and Experimental Hematology

• Gebundenes Buch

Produktbeschreibung

A vital resource on blood and bone marrow cell morphology inlaboratory animal medicine. This fully revised new edition is anessential reference for clinical pathologists in diagnosticlaboratories, and medical or veterinary research. The atlascontains over 400 color images of cells from the peripheral bloodand bone marrow from a variety of animals encountered in laboratoryanimal medicine, in health and disease.
Key features:

New chapter on flow cytometry and its application in terms ofroutine analyses as a means of identifying abnormalities in cellmarker expression, which is of particular relevance forpre-clinical safety assessment
Covers the most recent developments in laboratory animalhematology, including parameters measured by the latest generationof analyzers
Coverage of a wide range of laboratory animal species, as wellas those used in clinical veterinary trials
Photomicrographs present normal and abnormal blood cells from avariety of hematological conditions along with descriptivetext

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Produktdetails

• Verlag: Wiley & Sons
• Artikelnr. des Verlages: 1A405171070
• 2. Aufl.
• Seitenzahl: 160
• Erscheinungstermin: 15. August 2011
• Englisch
• Abmessung: 286mm x 225mm x 14mm
• Gewicht: 747g
• ISBN-13: 9781405171076
• ISBN-10: 1405171073
• Artikelnr.: 32717983

Autorenporträt

Clifford Smith is Chief Laboratory Scientist in the Haematology Department, and Head of Logistics, Clinical Pathology Services, at Covance Laboratories in Harrogate, UK. Alfred Jarecki is Principal Research Scientist with Sanofi-Aventis at the Alnwick Research Centre, UK.

Inhaltsangabe

Foreword vii Introduction ix Dedication xi Acknowledgments xiii 1 Rodents 1
Mouse 1 Introduction 1 Blood picture 1 Typical ranges (Siemens Advia 120) 2
Hamster 15 Introduction 15 Blood picture 15 Guinea Pig 17 Introduction 17
Blood picture 17 Rat - Sprague Dawley (SD)/Han Wistar (HW) 18 Introduction
18 Blood picture 18 Typical ranges (Siemens Advia 120) 19 References 36 2
Rabbit 37 Introduction 37 Blood picture 37 References 39 3 Cat 41
Introduction 41 Blood picture 41 References 44 4 Dog 45 Introduction 45
Blood picture 45 Typical ranges (Siemens Advia 120) 46 References 64 5
Monkey 65 Introduction 65 Blood picture 65 Marmoset 66 Cynomolgus 71
Introduction 71 Blood picture 71 Typical ranges (Siemens Advia 120) 72
Baboon 84 Rhesus Monkey 86 References 87 6 Other species 89 Pig 89
Introduction 89 Blood picture 89 Horse 91 Introduction 91 Blood picture 91
Goat and Sheep 94 Assorted Other Species 96 References 103 7 Blood
collection procedures 105 Common bleeding sites 105 Anticoagulants 105
Staining 105 8 Artifacts 107 Collection artifacts 107 Sample transport and
storage 109 Anticoagulant 110 Storage artifacts 111 Blood smear preparation
113 Stain precipitate 113 References 114 9 Bone marrow 115 Introduction 115
Review of marrow sampling techniques 115 Recommended methods for marrow
sampling 116 Preparation and staining of smears 118 Evaluation 119
Interpretation 119 References 120 10 Comparative applications in flow
cytometry 121 Application of fl ow cytometry in comparative hematology 122
References 132 Index 135