ATP-Binding Cassette Transporter

Herausgegeben:Miller, Frederic P.; Vandome, Agnes F.; McBrewster, John

• Broschiertes Buch

Produktbeschreibung

ATP-binding cassette transporters (ABC-transporter) are members of a protein superfamily that is one of the largest and most ancient families with representatives in all extant phyla from prokaryotes to humans.ABC transporters are transmembrane proteins that utilize the energy of adenosine triphosphate (ATP) hydrolysis to carry out certain biological processes including translocation of various substrates across membranes and non-transport- related processes such as translation of RNA and DNA repair.They transport a wide variety of substrates across extra- and intracellular membranes, including metabolic products, lipids and sterols, and drugs. Proteins are classified as ABC transporters based on the sequence and organization of their ATP-binding cassette (ABC) domain(s). ABC transporters are involved in tumour resistance, cystic fibrosis, bacterial multidrug resistance, and a range of other inherited human diseases.

Produktdetails

• Verlag: Alphascript Publishing
• Seitenzahl: 128
• Englisch
• ISBN-13: 9786130287436
• ISBN-10: 6130287437
• Artikelnr.: 28187615