SHOENFELD

Autoimmunity, Part a

Basic Principles and New Diagnostic Tools, Volume 1109
Herausgeber: Gershwin, M Eric; Bragazzi, Nicola Luigi

• Broschiertes Buch

Produktbeschreibung

The incidence of autoimmune diseases is increasing worldwide, and the search for better management of these diseases and even for a cure is being pursued by scientists from many disciplines. Tools from the areas of genetics, neuroscience, cell biology, virology, and infectious disease are being applied to the problem and are yielding useful results. This volume contains the first section of the proceedings of a large, comprehensive meeting held in Sorrento, Italy. Because the meeting focused on such an important area of human health, four volumes have been dedicated to it: Part A presents new principles in autoimmunity, including the roles of key players such as designed ankyrin repeat proteins, SLAM-associated protein, interleukin-12, human proteinase 3, the complement system, IgG, disturbances in cytokine synthesis, and IFN-γ blockers. The second section of the volume takes a look at new diagnostic tools, including screening of endothelial expression libraries, electrical skin impedance, and IgA anti-tissue transglutaminase antibody assays. Autoimmunity, Part B continues the presentation of basic research and its applications with a focus on genetics. Parts C and D present the clinical research in various manifestations of autoimmune disease and its treatments. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member.

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Produktdetails

• Verlag: Wiley
• Seitenzahl: 400
• Erscheinungstermin: 4. September 2007
• Englisch
• Abmessung: 229mm x 152mm x 31mm
• Gewicht: 834g
• ISBN-13: 9781573316637
• ISBN-10: 1573316636
• Artikelnr.: 22758530

Autorenporträt

M. Eric Gershwin is the editor of Autoimmunity, Part A: Basic Principles and New Diagnostic Tools, Volume 1109, published by Wiley. Yehuda Shoenfeld is an Israeli physician and autoimmunity researcher.

Inhaltsangabe

Foreword (M. Eric Gershwin and Yehuda Shoenfeld). Part I: New Principles of Autoimmunity. 1. The Nature and Nurture of Common Autoimmunity (John Castiblanco and Juan-Manuel Anaya). 2. Designed Ankyrin Repeat Proteins as Anti-Idiotypic Binding Molecules (Monique Vogel
Elsbeth Keller-Gautschi
Michael J. Baumann
Patrick Amstutz
Christine Ruf
Franz Kricek
Beda M. Stadler). 3. SLAM-Associated Protein (SAP) Solves a Mystery of Autoimmunity: (Shigemasa Sawada
Masami Takei
Tetsuyosi Ishiwata
Hidetaka Shiraiwa
Hirotake Inomata
Takamasa Nozaki). 4. Standardization of Autoimmune Diagnostics in Germany - Activities of the German Group in the European Autoimmune Standardisation Initiative (Ulrich Sack
Karsten Conrad
Elena Csernok
Ingrid Frank
Michael Haass
Torsten Krieger
Michael Seyfarth
Udo Schlosser
Reinhold E. Schmidt
Torsten Witte). 5. Autoimmunity and Time Entanglement (Juan I. Poo
Pablo I. Martin
Enrique Rewald). 6. The Pro- and Anti-Inflammatory Potential of Interleukin-12 (Hyun-Dong Chang
Andreas Radbruch). 7. NKG2D and Natural Cytotoxicity Receptors Are Involved in Natural Killer Cell Interaction with Self-Antigen Presenting Cells and Stromal Cells (Poggi Alessandro
Prevosto Claudia
Zancolli Marta
Paolo Canevali
Alessandra Musso
Zocchi Maria Raffaella). 8. The Role of Toll-Like Receptors in HMGB1 Release from Macrophages (David S. Pisetsky
Weiwen Jiang). 9. Immune Complex Pathophysiology (Urs E. Nydegger). 10. Human Proteinase 3 (PR3) and Its Binding Molecules: Implications for Inflammatory and PR3-Related Autoimmune Responses (Antje Müller
Jan Voswinkel
Stefan Gottschlich
Elena Csernok). 11. Loss of Self-Control in the Complement System and Innate Autoreactivity (Seppo Meri). 12. Immunodeficiency and Autoimmune Phenomena in Female Hyper IgM Syndrome (HIGM) (Melegari Alessandra
Mascia Maria Teresa
Sandri Gilda
Carbonieri Anna). 13. Autoimmune Diseases of Domestic Animals (Laurel J. Gershwin). 14. Prediction and Prevention of Autoimmune Disease: A Personal Perspective (Noel R. Rose). 15. Alterations of Th1/Th2 Reactivity by Heavy Metals: Possible Consequences Include Induction of Autoimmune Diseases (Nasr Y.A. Hemdan
Frank Emmrich
Sonya Faber
Ulrich Sack). 16. EASI - The European Autoimmunity Standardisation Initiative: A New Initiative That Can Contribute to Agreed Diagnostic Models of Diagnosing Autoimmune Disorders Throughout Europe (Yehuda Shoenfeld
Ricard Cervera
Michael Haass
Cees Kallenberg
Munther Khamashta
Pier Luigi Meroni
Jean-Charles Piette
Reinhold Schmidt
Allan Wiik). 17. Effector Memory CD8+ T Cells Are Resistant to Apoptosis (Sudhir Gupta
Sastry Gollapudi). 18. Two-Step Mechanism of Virus-Induced Autoimmune Hemolytic Anemia (Jean-Paul Coutelier
Laurent Detalle
Andrei Musaji
Mory Meite
Shozo Izui). 19. Autoimmune Reactions After Electro-Oxidation of IgG from Healthy Persons. Relevance of Electric Current and Antioxidants (Borut Bozic
Sasa Cucnik
Tanja Kveder
Blaz Rozman). 20. Autoimmune Diseases Are Connected With Disturbances In Cytokine Synthesis and Therapy With IFN-g Blockers Is Their Main Pathogenetic Treatment (Boris Skurkovich
Simon Skurkovich). Part II: New Tools in Diagnosis. 21. Screening of Endothelial Expression Libraries for the Identification of Novel Autoantigens Involved in Distinct Autoimmune Diseases Characterized by Endothelial Dysfunction (Paola Margutti
Federica Delunardo
Tania Colasanti
Ettore Piro
Elisabetta Profumo
Rachele Riganò
Alessandra Siracusano
Brigitta Buttari
Fabrizio Conti
Cristiano Alessandri
Antonella Capozzi
Maurizio Sorice
Elena Ortona). 22. Diagnosing Diseases by Mesurement of Electrical Skin Impedance: A Novel Technique (Rony Weitzen
Nava Epstein
Yehuda Shoenfeld
Eyal Zimlichman). 23. Antigen Preparation for Immunological Studies in Systemic Autoimmune Diseases (Sandra Zampieri
Anna Ghirardello
Katia Rossini
Luca Iaccarino
Nicola Bassi
Fabiola Atzeni
PierCarlo Sarzi-Puttini
Andrea Doria). 24. Comparison of Two Elisa Assays for Anti-SP100 Determination (José Manuel Lucena
Marcos Montes Cano
José Luis Caro
Nieves Respaldiza
Antonia Alvarez
Julio Sánchez-Román
Antonio Núñez-Roldán
Ingeborg Wichmann). 25. Diagnostic Accuracy of IgA Anti-Tissue Transglutaminase Antibody Assays in Celiac Disease Patients with Selective IgA Deficiency (D. Villalta
M.G. Alessio
M. Tampoia
E. Tonutti
I. Brusca
M. Bagnasco
G. Pesce
N. Bizzaro). 26. Anti-Topoisomerase 1 Antibodies in Systemic Sclerosis: How to Improve the Detection (Mathieu C. Tamby
Guillaume Bussone
Luc Mouthon). 27. The Effect of Open Heart Surgery on Tuberculin Skin Test Reactivity (Michal Stein
Batia Sela-Razon
Ilan Linder
Eli Somekh). 28. The Reliability of Control Skin Tests with Common Antigens in Children Undergoing Tuberculin Skin Test (Michal Stein
Batia Sela-Razon
Yeshayaou Kleter
Eli Somekh). 29. Ena Screen Chemiluminescence Immunoassay: A Random Access Method in Autoimmunology (S. Signorini
I. Kutschera
F. Capuano
L. Lattuada). 30. Evaluation of the BioPlex 2200(TM) ANA Screen for the Detection of Anti-Nuclear Antibodies and Comparison with Conventional Methods (Sophie Desplat-Jego
Nathalie Bardin
Bruno Larida
Marielle Sanmarco). 31. A New Line Immunoassay for the Multiparametric Detection of Anti-Ganglioside Autoantibodies in Patients with Autoimmune Peripheral Neuropathies (Karsten Conrad
Hauke Schneider
Tjalf Ziemssen
Thomas Talaska
Dirk Reinhold
Rene-Louis Humbel
Dirk Roggenbuck). 32. Lipocalin-2
Tweak and Other Cytokines as Urinary Biomarkers for Lupus Nephritis (Noa Schwartz
Jennifer S. Michaelson
Chaim Putterman). 33. The Prevalence of Anti-Nucleosome Antibodies by Enzyme-Linked Immunosorbent Assays (ELISA) in Patients with Systemic Lupus Erythematosus and Other Autoimmune Systemic Diseases (I. Putova
C. Dostal
R. Becvar). 34. Predictive Value of Antibodies to Citrullinated Peptides and Rheumatoid inbFactors Treated Patients (Francesca Bobbio-Pallavicini
Roberto Caporali
Anti-TNF- Claudia Alpini
Remigio Moratti
Carlomaurizio Montecucco). 35. Redox-Reactive Autoantibodies in Cerebrospinal Fluids (John A. McIntyre
Ronald L. Hamilton
Steven T. DeKosky). 36. Determination of Oxidized Low-Density Lipoproteins 2GPI Complexes for the (OxLDL) Versus OxLDL/ Atherosclerosis (Luis R.bAssessment of Autoimmune-Mediated Lopez
Tammmy R. Buckner
Beth L. Hurley
Kazuko Kobayashi
Eiji Matsuura). 37. Serological and Clinical Characterization of Anti-dsDNA and Anti-PM/Scl Double Positive Patients (M. Mahler
E.L. Greidinger
M. Szmyrka
A. Kromminga
M.J. Fritzler). 38. Performance of ANA CTD Screen as Screening for Connective Tissue Diseases (Marcos López-Hoyos
Vicente Rodríguez-Valverde
Victoria Martinez-Taboada). 39. Multiplex Assays to Diagnose Celiac Disease (Ivo Lochman
Peter Martis
Rufus W. Burlingame
Alexandra Lochmanová). 40. Could Serum Antibody to Poly(ADP-ribose) and/or Histone H1 be Marker for Senile Dementia of Alzheimer Type (Y. Kanai
H. Akatsu
H. Iizuka
C. Morimoto). 41. Identification by Proteomic Tool of Atypical Anti-Liver/Kidney-Microsome Autoantibodies Targets in de novo Auto-Immune Hepatitis After Liver Transplantation (S. Huguet
J. Vinh
C. Johanet
D. Samuel
M. Gigou
O. Zamfir
J.C. Duclos-Vallee
E. Ballot). 42. Automatic Analysis of Immunofluorescence Patterns of HEP-2 Cells (Rico Hiemann
Nadja Hilger
Jörg Michel
Jörg Nitschke
Alexander Böhm
Ursula Anderer
Martin Weigert
Ulrich Sack). 43. Exploring cDNA Phage Display for Autoantibody Profiling in Serum of Multiple Sclerosis Patients: Optimization of the Selection Procedure (C. Govarts
K. Somers
R. Hupperts
P. Stinissen
V. Somers). 44. Novel Biomarkers in Autoimmune Diseases Prolactin
Ferritin
Vitamin D and TPA Levels in Autoimmune Diseases (Hedi Orbach
Gisele Zandman-Goddard
Howard Amital
Vivian Barak
Zoltan Szekanecz
Gabriella Szucs
Katalin Danko
Endre Nagy
Tunde Csepany
Jozelio F. Carvalho
Andrea Doria
Yehuda Shoenfeld). 45. Evaluation of Current Methods for the Measurement of Serum Anti-Double Stranded DNA Antibodies (Anna Ghirardello
Danilo Villalta
Gabriella Morozzi
Antonella Afeltra
Mauro Galeazzi
Robert Gerli
Alessandro Mathieu
Pier Luigi Meroni
Paola Migliorini
Antonella Radice
Valeria Riccieri
Amelia Ruffatti
Gian Domenico Sebastiani
Angela Tincani
Andrea Doria). 46. Evaluation of the Liaison ANA Screen Assay for Antinuclear Antibody Testing in Autoimmune Diseases (P. Ghillani
A.M. Rouquette
C. Desgruelles
N. Hauguel
C. Le Pendeven
J.C. Piette
L. Musset). 47. Clinical Significance of Anti-Histidyl-tRNA Synthetase (Jo1) Autoantibodies (Emeline Gomard-Mennesson
Nicole Fabien
Jean-Francois Cordier
Jacques Ninet
Jacques Tebib
Hugues Rousset). 48. Antinucleosome Antibodies and Systemic Lupus Erythematosus (Nursen Düzgün
Mehmet Sahin
Yasemin Genç
Hüseyin Tutkak). 49. Protein Expression Profile of Celiac Disease Patient with Aberrant T-Cell By Two-Dimensional Difference Gel Electrophoresis (Valli De Re
Maria Paola Simula
Laura Caggiari
Nicoletta Ortz
Michele Spina
Alessandro Da ponte
Leandro De Appolonia
Riccardo Dolcetti
Vincenzo Canzonieri
Renato Cannizzaro). 50. The Chemokine Profile of the Different Inflammatory Myopathies Reflects the Humoral Versus Cytotoxic Immune Responses (Boel De Paepe
Kim K. Creus
Jan L De Bleecker). 51. Evaluation of the FIDIS Multiplex Immunoassay for Diagnosis and Follow-Up of ANCA-Associated Vasculitis and Goodpasture's Disease (J. Damoiseaux
M. Vaessen
Y. Knapen
E. Csernok
C.A. Stegeman
P. van Paassen
J.W. Cohen Tervaert). 52. Comparison of Three Multiplex Immmunoassays for Detection of Antibodies to Extractable Nuclear Antibodies Using Clinically Defined Sera (Susan S. Copple
Thomas B. Martins
Charlin Masterson
Erwann Joly
Harry R. Hill). 53. Identification of Histidine-Rich Glycoprotein
a Potential Autoantigen
in Human and Rat Brain Preparations (Catrin Ball-Rosen
Hagit Primak-Rubinovicz
Amos D. Korczyn
Ningshan Wang
Adel Farchi
Sara Shavit
Yehuda Shoenfeld
Joab Chapman). 54. An Analysis of Experimental 2Glycoprotein I Elisa Assay Results: Conditions Influencing the Anti- (Anna Cavazzana
Amelia Ruffatti
Marta Tonello
bAnna Maria Bortolati
Philippe de Moerloose
Guido Reber). 55. Development of Automated Assays for Anti Cardiolipin Antibodies Determination: Addressing Antigen/Solid-Phase and Standardization Issues (Francesco Capuano
Valentina Grasso
L. Belforte
Luca Pallavicini
Fabrizio Bonelli). 56. Biological and Clinical Relevance of Anti-Prothrombin Antibodies (Anna Ghirardello
Nicola Bizzaro
Sandra Zampieri
Luca Iaccarino
Nicola Bassi
Renato Tozzoli
Amelia Ruffatti
Danilo Villalta
Elio Tonutti
Andrea Doria). 57. Clinical Evaluation of a New Quantitative Enzyme Linked Immunosorbent Assay for Detection of Double Stranded DNA Autoantibodies (Nathalie Bardin
Celine Ragot
Marielle Sanmarco). 58. Characterization of Autoantibodies Against Components of the Nuclear Pore Complexes: High Frequency of Anti-p62 Nucleoporin Antibodies (Jozefa Wesierska-Gadek
Anna Klima
Oxana Komina
Carmen Ranftler
Pietro Invernizzi
Edward Penner). 59. Anti-Cardiolipin and Anti-Beta2Glycoprotein-I Antibdies: Performance of New Commercial Elisa Kits (Laura Andreoli
Fabio Malacarne
Angela Ceribelli
Iris Kutschera
Angela Tincani). 60. A Combined SDS-PAGE and Proteomics Approach to Identify Target Autoantigens in Healthy Individuals and Patients with Autoimmune Diseases (Philippe Guilpain
Amélie Servettaz
Mathieu C. Tamby
Youri Chanseaud
Nicolas Tamas
Paloma Garcia de la Pena-Lefebvre
Cédric Broussard
Luc Camoin
Luc Mouthon). 61. Anti-Vitamin D
Vitamin D in SLE: Preliminary Results (Jozélio Freire de Carvalho
Miri Blank
Emese Kiss
Tunde Tarr
Howard Amital
Yehuda Shoenfeld). Index of Contributors.