Mothers' decision is a major factor(s) that affect immunization schedule in sub-Sahara and Africa. Ghana is not different from these countries. This book focus on Ghanaian mothers perspectives, attitudes, practices and awareness towards immunization and how attendance of child welfare clinic facilitate the uptake of immunization of their children. The mothers' attitudes towards immunization were high but awareness about it was poor. Therefore, there was the need for all stakeholders to intensify, educate and communicate the significance of immunization through various medium at their disposal at all levels of healthcare.