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Cotton (Gossypium spp.) belongs to family malvaceae is one of the important cash, fibre and oilseed crop commonly grown in many parts of India.Bacterial blight disease incited by Xanthomonas axonopodis pv. malvacearum is a serious threat to successful cultivation of cotton wherever the crop is grown. Bacterial blight disease severity (PDI) and disease incidence (PI) in chemical management studies conducted in vivo.Amongst the antagonist tested against this bacteria Trichoderma hamatum was significantly superior in per cent reduction of mycelia colony diameter (mm) of pathogen at all the incubation periods tested. .Amongst the chemical tested against this bacteria, copper oxychloride 0.25% +streptocycline 100 ppm was significantly superior in per cent reduction of mycelia colony diameter (mm) of pathogen at all the incubation periods tested. The next best chemical noticed was carbendazim 0.1% and copper oxychloride 0.25% + agrimycin 100 ppm.Screening of total 36 genotypes of cotton under natural condition of infection none showed immune, none showed resistant, while 3 genotypes were moderately resistant, 31 were moderately susceptible and 2 were susceptible against bacterial blight