Fanos Tadesse Woldemariyam

Bacterial Virulence Factors, Secretion of Virulence Protein

Bacterial Virulence Factors and Secretion of Virulence Protein and their Mechanism of Action

• Broschiertes Buch

Produktbeschreibung

Bacterial cells must transport proteins across their membranes for the biogenesis of membranes and cell walls, motility and nutrient scavenging and uptake, and is also involved in pathogenesis and symbiosis. The translocase is an impressively dynamic nanomachine that is the central component which catalyses trans-membrane crossing. This complex, multi-stage reaction involves a cascade of inter- and intra-molecular interactions that select, sort and target polypeptides to the membrane, and in addition, transport through the outer membrane requires ATP or other sources of energy to promote the movement of these polypeptides across or their lateral escape and integration into the phospholipid bilayer, with high fidelity and efficiency. Here, the review addresses the structure and function of the translocase nanomachine and different mechanisms of protein secretion and their transport.The general secretion Sec and twin arginine translocation (Tat) pathways are the bacterial secretionsystems most commonly used to transport proteins across the cytoplasmic membrane.Often, Sec or Tat systems transport unfolded and folded proteins first to the periplasmic space in Gram negative bacteria.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 100
• Erscheinungstermin: 10. September 2019
• Englisch
• Abmessung: 220mm x 150mm x 6mm
• Gewicht: 167g
• ISBN-13: 9786200307729
• ISBN-10: 6200307725
• Artikelnr.: 57875280

Autorenporträt

Persönliche Daten: Name Fanos Tadesse Woldemariyam Geschlecht Männlich Geburtsdatum 07/09/1978 Geburtsort Bale-Jara, Äthiopien Staatsangehörigkeit Äthiopisch