Barriers and Channels Formed by Tight Junction Proteins II, Volume 1258

Herausgeber: Fromm, Michael; Schulzke, Jörg-Dieter

• Broschiertes Buch

Produktbeschreibung

"Tight junctions between epithelial and endothelial cells form selective barriers and paracellular channels and regulate paracellular transport of solutes, immune cells, and drugs. More specifically, tight junctions consist of proteins that laterally interconnect neighboring cells of epithelia and endothelia. Certain proteins seal the tight junction, so that a nearly impermeable barrier develops, whereas others form channels that allow for permeation between the cells. Recent investigations have focused on tight junction proteins, belonging to the claudin family (claudins-1 to -27 in humans) and the newly defined group of TAMP (three proteins: occludin, Marvel-D2, and tricellulin). Barriers and Channels Formed by Tight Junction Proteins I showcases work in this area clustered around three major themes: the molecular properties of tight junctions, for example, the role of the claudin family of proteins and the formation of ion and charge-selective channels; the regulation of tight junction and barrier functions via genetic mechanisms and scaffold protein mediation; and the functional role of the tight junction in various tissues, such as the skin, lungs, endothelia, and nervous system"--Publisher description.

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Produktdetails

• Verlag: Wiley
• Seitenzahl: 191
• Erscheinungstermin: 24. Juli 2012
• Englisch
• Abmessung: 249mm x 175mm x 10mm
• Gewicht: 363g
• ISBN-13: 9781573318921
• ISBN-10: 1573318922
• Artikelnr.: 36152305

Autorenporträt

Michael Fromm is the editor of Barriers and Channels Formed by Tight Junction Proteins II, Volume 1258, published by Wiley. Jörg-Dieter Schulzke is the editor of Barriers and Channels Formed by Tight Junction Proteins II, Volume 1258, published by Wiley.

Inhaltsangabe

TNF-[alpha]-induced intestinal epithelial cell shedding : implications for
intestinal barrier function / Alastair J.M. Watson and Kevin R. Hughes
Tight junctions on the move : molecular mechanisms for epithelial barrier
regulation / Le Shen
HIV infection and the intestinal mucosal barrier / Hans-Jörg Epple and
Martin Zeitz
Zonulin, regulation of tight junctions, and autoimmune diseases / Alessio
Fasano
Myosin light chain kinase : pulling the strings of epithelial tight
junction function / Kevin E. Cunningham and Jerrold R. Turner
Defective tight junctions in refractory celiac disease / Michael Schumann
[and others]
Microbial butyrate and its role for barrier function in the
gastrointestinal tract / Svenja Plöger [and others]
SUMOylation of claudin-2 / Christina M. Van Itallie, Laura L. Mitic and
James M. Anderson
Proof of concept for claudin-targeted drug development / Hidehiko Suzuki
[and others]
Loss of enteral nutrition in a mouse model results in intestinal epithelial
barrier dysfunction / Yongjia Feng [and others]
The protein C pathway in intestinal barrier function : challenging the
hemostasis paradigm / Silvia D'Alessio, Marco Genua and Stefania Vetrano
Analysis of absorption enhancers in epithelial cell models / Rita Rosenthal
[and others]
Calcium regulation of tight junction permeability / Markus Bleich, Qixian
Shan and Nina Himmerkus
Effects of quercetin studied in colonic HT-29/B6 cells and rat intestine in
vitro / Maren Amasheh [and others]
Claudin-based paracellular proton barrier in the stomach / Atsushi Tamura
[and others]
Regulation of epithelial proliferation by tight junction proteins / Attila
E. Farkas, Christopher T. Capaldo and Asma Nusrat
Barrier dysfunction and bacterial uptake in the follicle-associated
epithelium of ileal Crohn's disease / A¿sa V. Keita and Johan D. Söderholm
The protozoan pathogen Toxoplasma gondii targets the paracellular pathway
to invade the intestinal epithelium / Caroline M. Weight and Simon R.
Carding
Ion transport and barrier function are disturbed in microscopic colitis /
Christian Barmeyer [and others]
Enteropathogenic E. coli effectors EspG1/G2 disrupt tight junctions : new
roles and mechanisms / Lila G. Glotfelty and Gail A. Hecht
Abnormal intestinal permeability in Crohn's disease pathogenesis /
Christopher W. Teshima, Levinus A. Dieleman and Jon B. Meddings
A dynamic paracellular pathway serves diuresis in mosquito Malpighian
tubules / Klaus W. Beyenbach
Impaired paracellular ion transport in the loop of Henle causes familial
hypomagnesemia with hypercalciuria and nephrocalcinosis / Lea Haisch and
Martin Konrad
The yin and yang of claudin-14 function in human diseases / Jianghui Hou