The foundation of Bioinformatics is the information stored in various databases. It is a larger science in Computational biology, which is having wide area of applications in quantitative analytical techniques in modeling and solving various problems in biological systems. "Basics in Bioinformatics" provides theoritical and practical approaches in understanding of hidden biological information by using Computers. Topics such as Biology, Biological databases, Sequence alignment, Protein structure prediction, Molecular modeling, Drug designing, Systems biology and recent advances in Bioinformatics provides the way by utilizing the knowledge of biomolecules with Information Technologies. This book covers the core topics in present research areas of Bioinformatics.