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The phytochemical and biological activities in Paulownia tomentosa (Thunb.) Steud., for the first time in Egypt. The study revealed the presence of biologically active constituents viz, volatile oil, sterols, iridoids, triterpenes, phenolics and flavonoids. In the present study we have assessed the inhibitory effects of Paulownia tomentosa (Thunb.) Steud. flowers, fruits and the isolated ursolic acid on hepatocarcinogenesis for the first time using a diethyl nitrosamine induced rats and group treated with the isolated ursolic acid showed the most significant results during the study, also…mehr

Produktbeschreibung
The phytochemical and biological activities in Paulownia tomentosa (Thunb.) Steud., for the first time in Egypt. The study revealed the presence of biologically active constituents viz, volatile oil, sterols, iridoids, triterpenes, phenolics and flavonoids. In the present study we have assessed the inhibitory effects of Paulownia tomentosa (Thunb.) Steud. flowers, fruits and the isolated ursolic acid on hepatocarcinogenesis for the first time using a diethyl nitrosamine induced rats and group treated with the isolated ursolic acid showed the most significant results during the study, also group treated with P. tomentosa fruits showed remarkable results. The hepatoprotective activity of Paulownia tomentosa (Thunb.) Steud. fruits was attributed to the isolated aucubin which was reported to have potent liver protecting activity. The hypoglycemic effect of the leaves and fruits of Paulownia tomentosa (Thunb.) Steud., on normoglycemic and hyperglycemic rats was carried out for the first time.
Autorenporträt
Sanaa Ahmed Ali, M.Sc and Ph.D Faculty of science, Ain Shams University. Professor of Biochemistry Theraputic Chemistry Department National Research Centre; Laila M.Faddah Professor of Pharmacology,Dep.of Pharmacology,Faculty of Pharmacy King Saud University; Maiiada Hassan Nazmy Lecturer of Biochemistry,Faculty of Pharmacy El-Minia University.