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Controlling obesity and other comorbidities in the population is a challenge in modern society. High-intensity interval training (HIIT) combines short periods of high-intensity exercise with long recovery periods or a low-intensity exercise. The aim was to assess the impact of HIIT in the context of diet-induced obesity in the animal model. C57BL/6 mice were fed one of the two diets: standard chow or a high-fat diet. After 12 weeks, the animals were divided into non-trained and trained groups, and began an exercise protocol. HIIT leads to significant reductions in body mass, blood glucose,…mehr

Produktbeschreibung
Controlling obesity and other comorbidities in the population is a challenge in modern society. High-intensity interval training (HIIT) combines short periods of high-intensity exercise with long recovery periods or a low-intensity exercise. The aim was to assess the impact of HIIT in the context of diet-induced obesity in the animal model. C57BL/6 mice were fed one of the two diets: standard chow or a high-fat diet. After 12 weeks, the animals were divided into non-trained and trained groups, and began an exercise protocol. HIIT leads to significant reductions in body mass, blood glucose, glucose tolerance and hepatic lipid profile in T-groups compared to NT-groups. HIIT was able to reduce plasma levels of inflammatory cytokines. Additionally, HIIT improves the insulin immunodensity in the islets, reduces the adiposity and the hepatic steatosis in the T-groups. HIIT improves beta-oxidation and peroxisome proliferator-activated receptor (PPAR) alpha and reduces lipogenesis and PPAR gamma levels in the liver. In muscle, improves PPAR alpha and GLUT 4 and reduces PPAR gamma levels. HIIT leads to attenuate the adverse effects caused by a chronic ingestion of a high-fat diet.
Autorenporträt
PhD student of the Post-graduation program in Human Biology and Experimental (UERJ), Master of Science in Laboratory of Morphometry, Metabolism and Cardiovascular Disease (LMMC) and Graduation in Physical Education (Full Degree). Performance in strength training and resistance, metabolic syndrome, obesity and oxidative stress (cell damage).