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Many neurodegenerative diseases are related to neuronal death, mainly to oxidative stress. Several studies show that hydrogen peroxide can cause cell damage resulting in neuronal death, but at the same time, other research indicates that hydrogen peroxide, at low concentrations, can participate in the activation of neuronal survival pathways or act as a neuromodulator in the activity of neuronal cells. The purpose of the present study was to evaluate the in vitro effect of hydrogen peroxide on neuronal cell cultures and the activation of the enzyme neuronal nitric oxide synthase through…mehr

Produktbeschreibung
Many neurodegenerative diseases are related to neuronal death, mainly to oxidative stress. Several studies show that hydrogen peroxide can cause cell damage resulting in neuronal death, but at the same time, other research indicates that hydrogen peroxide, at low concentrations, can participate in the activation of neuronal survival pathways or act as a neuromodulator in the activity of neuronal cells. The purpose of the present study was to evaluate the in vitro effect of hydrogen peroxide on neuronal cell cultures and the activation of the enzyme neuronal nitric oxide synthase through neuromodulation of the MAPK-ERK1/2 mitogenic and neuronal survival signaling pathways.
Autorenporträt
Biologiste, diplômé de l'université nationale de San Agustín (Pérou), professionnel spécialisé dans le domaine biomédical. Exécution de procédures et de techniques analytiques développées dans le laboratoire d'analyse clinique, biologique et connexe, à des fins de prévention, de diagnostic, de thérapie et de contrôle de l'évolution des maladies.