Biodrug Delivery Systems

Fundamentals, Applications and Clinical Development
Herausgeber: Morishita, Mariko; Park, Kinam

• Broschiertes Buch

Produktbeschreibung

Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development presents the work of an international group of leading experts in drug development and biopharmaceutical science who discuss the latest advances in biodrug delivery systems and associated techniques. The book discusses components of successful formulation, delivery, and production of biodrugs, which include sophisticated plants and complex processes, a well-trained and knowledgeable staff, and proper quality control. In addition, the authors examine: ADME (Absorption, Metabolism, Distribution, and Elimination of biodrugs) Directing and influencing the successful development of currently marketed best-selling biodrugs Routes of administration Mechanisms of biodrug absorption Alternative possibilities for drug delivery routes Formulationson the market from the perspective of industry personnel involved in biodrug development

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Produktdetails

• Verlag: CRC Press
• Seitenzahl: 488
• Erscheinungstermin: 16. Juni 2017
• Englisch
• Abmessung: 229mm x 152mm x 26mm
• Gewicht: 700g
• ISBN-13: 9781138116795
• ISBN-10: 1138116793
• Artikelnr.: 49782484

Autorenporträt

Mariko Morishita, Kinam Park

Inhaltsangabe

1. Overview of Biodrug delivery system. 2. Issues in Biodrug delivery
system. 3. Pharmacokinetic consideration of Biodrugs. Specific Route of
Delivery. 1. Parenteral delivery. 2. Brain delivery. 3. Ocular delivery. 4.
Nasal delivery. 5. Buccal delivery. 6. Pulmonary delivery. 7. Transdermal
delivery. 8. Colon delivery. 9. Oral delivery. 10. Cellular delivery.
Delivery Systems. 1. Targeting: PK consideration. Monoclonal antibody.
Receptor-mediated endocytosis. 2. Bioadhesive delivery system. 3. Modified
release delivery system. 4. Nanoparticulate delivery system. 5. Lipid-based
delivery system. 6. Implantable delivery system. 7. Modifying the
physiochemical nature of Biodrugs. 8. Regulatory perspective of Biodrug
development. Development of Biodrug Products. 1. Leuplin. 2. ANP (atrial
natriuretic peptide). 3. Amylin and GLP-1 agonists. 4. GHRP-2 (growth
hormone releasing peptide. 5. Endothelin receptor antagonist. 6.
Angiotensin II receptor antagonist. 7. Insulin (inhalation). 8. Calcitonin
(nasal, etc.). 9. Sandstatin LAR. 10. Interferon. 11. Vaccine. Perspective
of Biodrug Products.