Biodrug Delivery Systems Fundamentals, Applications and Clinical Development Herausgeber: Morishita, Mariko; Park, Kinam
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Biodrug Delivery Systems Fundamentals, Applications and Clinical Development Herausgeber: Morishita, Mariko; Park, Kinam
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An international group of leading experts in drug development and biopharmaceutical science discusses the latest advances in biodrug delivery systems and associated techniques.
1. Overview of Biodrug delivery system. 2. Issues in Biodrug delivery system. 3. Pharmacokinetic consideration of Biodrugs. Specific Route of Delivery. 1. Parenteral delivery. 2. Brain delivery. 3. Ocular delivery. 4. Nasal delivery. 5. Buccal delivery. 6. Pulmonary delivery. 7. Transdermal delivery. 8. Colon delivery. 9. Oral delivery. 10. Cellular delivery. Delivery Systems. 1. Targeting: PK consideration. Monoclonal antibody. Receptor-mediated endocytosis. 2. Bioadhesive delivery system. 3. Modified release delivery system. 4. Nanoparticulate delivery system. 5. Lipid-based delivery system. 6. Implantable delivery system. 7. Modifying the physiochemical nature of Biodrugs. 8. Regulatory perspective of Biodrug development. Development of Biodrug Products. 1. Leuplin. 2. ANP (atrial natriuretic peptide). 3. Amylin and GLP-1 agonists. 4. GHRP-2 (growth hormone releasing peptide. 5. Endothelin receptor antagonist. 6. Angiotensin II receptor antagonist. 7. Insulin (inhalation). 8. Calcitonin (nasal, etc.). 9. Sandstatin LAR. 10. Interferon. 11. Vaccine. Perspective of Biodrug Products.