A comprehensive overview of the use of computational biology approaches in the drug discovery and development process.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Foreword; Preface: the future of drug discovery and health care Eric Schadt; 1. The art and science of the Drug Discovery Pipeline (DDP) William T. Loging; 2. Computational approaches to drug target identification Thomas B. Freeman and Pek Lum; 3. Understanding human disease knowledge through text mining Raul Rodriguez-Esteban; 4. Integrating translational biomarkers into drug development Jonathan Phillips; 5. Computational phenotypic assessment of small molecules in drug discovery William T. Loging and Thomas B. Freeman; 6. Data visualization and the DDP process Ke Xu; 7. Information visualization - important IT considerations Telmo Silva; 8. The New Drug Application (NDA) and regulatory approval stages William T. Loging, Marilyn Lewis, Bryn Williams-Jones and Roy Mansfield; 9. Clinical trial failures and drug repositioning Mark Crawford and Jeff Handler; Appendix I. Additional knowledge-based analysis approaches Raul Rodriguez-Esteban; Appendix II. Open source tools and public data sources Yirong Wang and William T. Loging; Index.
Foreword; Preface: the future of drug discovery and health care Eric Schadt; 1. The art and science of the Drug Discovery Pipeline (DDP) William T. Loging; 2. Computational approaches to drug target identification Thomas B. Freeman and Pek Lum; 3. Understanding human disease knowledge through text mining Raul Rodriguez-Esteban; 4. Integrating translational biomarkers into drug development Jonathan Phillips; 5. Computational phenotypic assessment of small molecules in drug discovery William T. Loging and Thomas B. Freeman; 6. Data visualization and the DDP process Ke Xu; 7. Information visualization - important IT considerations Telmo Silva; 8. The New Drug Application (NDA) and regulatory approval stages William T. Loging, Marilyn Lewis, Bryn Williams-Jones and Roy Mansfield; 9. Clinical trial failures and drug repositioning Mark Crawford and Jeff Handler; Appendix I. Additional knowledge-based analysis approaches Raul Rodriguez-Esteban; Appendix II. Open source tools and public data sources Yirong Wang and William T. Loging; Index.
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