The over all purpose of this book to provide information related to Staphylococcus aureus for researchers and scientist especially related to the magnitude of disease and Antimicrobial resistance. Moreover, the book will provide information on the automated system of Diagnosis of diseases which are actually comparable to molecular technique. Furthermore, the book will give us a comparative prevalence of staphylococcus aureus both in animal and humans who have contact with animals. Above all, It will give us the Antimicrobial resistance of commonly used twelve antimicrobial both in humans and animals.Therefore, I believe that It will a great advantage for the reader if they got these updated information on Staphylococcus aureus.