Biological activities of 1,3,4-oxadiazole Derivatives - Singh, Arvind kumar;Parthasarthy, R.
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1, 3, 4-Oxadiazole are heterocyclic compounds containing one oxygen & two nitrogen atom in a five membered ring. 1,3,4-oxadiazole derivatives have to placed a major role in the pharmaceutical chemistry .The number of so many synthetic compounds with oxadiazole nucleus used for antibacterial ,antifungal , analgesic and anti-inflammatory activities .Derivatives of 1,3,4-oxadiazole with suitable substitution at 2,5 position have been already reported to possible biological activities . 1,3,4-oxadiazole derivatives act as anticonvulsant & diuretics. These observation and our interest in the…mehr

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Produktbeschreibung
1, 3, 4-Oxadiazole are heterocyclic compounds containing one oxygen & two nitrogen atom in a five membered ring. 1,3,4-oxadiazole derivatives have to placed a major role in the pharmaceutical chemistry .The number of so many synthetic compounds with oxadiazole nucleus used for antibacterial ,antifungal , analgesic and anti-inflammatory activities .Derivatives of 1,3,4-oxadiazole with suitable substitution at 2,5 position have been already reported to possible biological activities . 1,3,4-oxadiazole derivatives act as anticonvulsant & diuretics. These observation and our interest in the pharmaceutical chemistry of heterocyclic compounds promoted us,we have synthesized different derivatives of,1,3,4-oxadiazole with different substituent at 2&5-position . These derivatives have been also screened for their anti-inflammatory activity.Mostly five membered aromatic system having three heteroatom s at symmetrical position have been studied because of their physiological properties.It is also well established that various derivatives of 1,3,4-oxadiazole exhibit broad spectrum of pharmacological properties such as antibacterial and anti-fungal activities.
Autorenporträt
Arvind kumar singh got M.Pharm (Pharmaceutical chemistry) form Biju patnaik university orissa and pursued PhD(Thesis submitted)from National institute of medical sciences(NIMS)Jaipur Rajasthan India.Presently he is working as assistant professor at KNIMT(faculty of pharmacy)sultanpur uttarpradesh india.