Dental caries is a localized post eruptive pathological process of external origin involving softening of the hard tooth tissue and proceeding to the formation of cavity as defined by WHO. It is the most prevalent disease in the humans and manifests with an extremely high caries index in several countries. In an attempt to widen as biologically and conservatively as possible several authors have suggested the use of tooth fragments or extracted human teeth as a restorative material to rehabilitate severely destroyed tooth crowns. The technique is simple, allows the preservation of sound tooth structure and provides excellent aesthetics. This book aims to review the evolution, methods and outcomes of these biological restorations.