Stephen J. Cutler (ed.)

Biologically Active Natural Products

Pharmaceuticals
Herausgeber: Cutler, Stephen J; Cutler, Horace G

• Gebundenes Buch

Produktbeschreibung

This book demonstrates the connections between agrochemicals and pharmaceuticals and explores the use of plants and plant products in the formulation and development of pharmaceuticals. TOC:Strategy for Rapid Identification of Novel Therapeutical Leads from Natural Products.- Oxidation Products of Dithiol and Cysteine Catalyzed by Rhus Laccase from Chinese Lacquer.- Review of Saponins Used in Foods, Agriculture, and Medicine.- Reactive Quinones: From Chemical Defense Mechanisms in Plants to Drug Design. Opiate-Derived Ligands as Phamacologic Tools and Potential Medicinal Agents.- Structure and Bioactivities of Oriental Lacquer Polysaccharides from Different Sources.- Structure-Activity Relationships of Peroxide-Based Artemisinin Antimalarials.- The Therapeutical Potential of Plant-Derived Compounds: Realizing the Potential.- Discovery of Antifungal Agents from Natural Sources: Virulence Factor Targets.- Naturally Occurring Antimutagenic and Cytoprotective Agents.- The Rainforest as Nature's Combinatorial Library.- The Design, Synthesis and Evaluation of Potential Human Complement Inhibitors Based on a Natural Product Model.- Fractionation of Plants to Discover Substances to Combat Cancer.- Highlights of Research on Plant-Derived Natural Prodcuts and Their Analogs with Antitumor, Anti-HIV, and Antifungal Activity.- Docking Study of 1-Chloro-2, 4-dinitrobenzene (CDNB) Binding at the Putative H-Site of Human Glutathione-S-Transferase Pi (GST-Pi) Polymorphic Proteins.- Nicotinic Agonists Based on Lobeline, Synthesis and Biological Evaluation.- Protein Kinase C Inhibitory Phenylpropanoid Glycosides from Polygonum Species.- Thwarting Resistance: Annonaceous Acetogenins as New Pesticidal and Antitumor Agents.- Isolation of Biologically Active Constituents of Papaver Somniferum, Erythroxylon Coca, and Cannabis Sativa.- Marine Natural Products as Antiinfective Agents.- Panax Ginseng: Standardisation and Biological Activity.- Commercialization of Plant-Derived Natural Products as Pharmaceuticals: A View from the Trenches.

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Produktdetails

• Verlag: CRC Press
• Seitenzahl: 296
• Erscheinungstermin: 27. Juli 1999
• Englisch
• Abmessung: 266mm x 180mm x 23mm
• Gewicht: 753g
• ISBN-13: 9780849318870
• ISBN-10: 0849318874
• Artikelnr.: 21125176

Autorenporträt

Stephen J. Cutler, Horace G. Cutler

Inhaltsangabe

Connections between Agrochemicals and Pharmaceuticals. Fractionation of
Plants to Discover Substances to Combat Cancer. Therapetuic Potential of
Plant-Derived Compounds: Realizing the Potential. Biodiversity
Conservation, Economic Development, and Drug Discovery in Suriname. Recent
Trends in the Use of Natural Products and Their Derivatives as Potential
Pharmaceutical Agents. Highlights of Research on Plant-Derived Natural
Products and Their Analogs with Antitumor, Anti-HIV, and Antifungal
Activity. Discovery of Antifungal Agents from Natural Sources: Virulence
Factor Targets. Reactive Quinones: From Chemical Defense Mechanisms in
Plants to Drug Design. Structure-Activity Relationships of Peroxide Based
Artemisinin Antimalarials. Naturally Occurring Antimutagenic and
Cytoprotective Agents. Lobeline: A Natural Product with High Affinity for
Neuronal Nicotinic Receptors and a Vast Potential for Use in Neurological
Disorders. Protein Kinase C Inhibitory Phenylpropanoid Glycosides from
Polygonum Species. Thwarting Resistance: Annonaceous Acetogenins as New
Pesticidal and Antitumor Agents. A Strategy for Rapid Identification of
Novel Therapeutic Leads from Natural Products. Dynamic Docking Study of the
Binding of 1-Chloro-2, 4-Dinitrobenzene in the Putative Electrophile
Binding Site of Naturally Occurring Human Glutathione S-Transferase Pi
Allelo-Polymorphic Proteins. Panax Ginseng: Standardization and Biological
Activity. Marine Natural Products as Leads to Develop New Drugs and
Insecticides. Commercialization of Plant-Derived Natural Products as
Pharmaceuticals: A View from the Trenches.