Biology of Mycobacterial Lipids

Herausgeber: Fatima, Zeeshan; Canaan, Stéphane

• Broschiertes Buch

Produktbeschreibung

Biology of Mycobacterial Lipids covers various topics pertaining to the advancements and current research in the field of mycobacterial lipids, and on the significant progress in lipidomics, in recent times. The chapters present comprehensive, yet systematic cutting-edge research, comprising mycobacterial lipid terminologies, classifications, biosynthetic pathways, tools and techniques, and functional burgeoning. This unique reference book has contributions from pioneer researchers, experts, and eminent veterans from around the globe. It covers ground-breaking work that will bridge the gap between understanding biochemical patterns related to virulence, pathogenesis, and resistance and elucidating new targets for drug design, identifying biomarkers for predicting risk, early diagnosis, and therapeutic outcome.

Produktdetails

• Developments in Microbiology
• Verlag: Elsevier Science & Technology
• Seitenzahl: 314
• Erscheinungstermin: 9. Juni 2022
• Englisch
• Abmessung: 191mm x 232mm x 27mm
• Gewicht: 626g
• ISBN-13: 9780323919487
• ISBN-10: 0323919480
• Artikelnr.: 63120824

Inhaltsangabe

1. An overview of mycolic acids: structure-function-classification,
biosynthesis, and beyond 2. Lipid biosynthetic pathways as potential drug
targets for emerging mycobacterial pathogens 3. Mycobacterial lipids in the
host-pathogen interface: roles in pathogenesis and host immune response 4.
Lipids and glycolipids as biomarkers of mycobacterial infections 5.
Multifaceted roles of mycobacterium cell envelope glycolipids during host
cell membrane interactions 6. Conserved mechanisms drive host-lipid access,
import, and utilization in Mycobacterium tuberculosis and M. marinum 7.
Biological implications of mycobacterial lipids on NKT-cells stimulation 8.
The effect of chemically synthetic mycobacterial mycolates on
phospholipidome immunomodulation of murine macrophages 9. Polyketide
synthases in mycobacterial lipid metabolism 10. Understanding mycobacterial
lipid metabolism and employing it as a tool to produce attenuated TB
vaccine candidates 11. Deciphering the physiological role of serine enzymes
involved in mycobacterial lipid metabolism using activity-based protein
profiling 12. Intrabacterial lipid inclusions: overview of an amazing
organelle 13. Multiple facets and functions of the toxin mycolactone
produced by Mycobacterium ulcerans