Growth assessment holds a very important place in the treatment planning of any orthodontic case. Various methods through the years have been developed to estimate as assess the amount of growth potential remaining in a growing patient. One of these methods is through the use of Biomarkers found in serum, saliva, GCF, Urine etc. These methods have gained popularity in modern orthodontic practice due to their non-invasiveness and minimal patient discomfort. The contents of this book describe these methods in detail with an aim of providing an ease to both the clinician and the patient.