Biomarkers
In Medicine, Drug Discovery, and Environmental Health
Herausgeber: Vaidya, Vishal S; Bonventre, Joseph V
Biomarkers
In Medicine, Drug Discovery, and Environmental Health
Herausgeber: Vaidya, Vishal S; Bonventre, Joseph V
- Gebundenes Buch
- Merkliste
- Auf die Merkliste
- Bewerten Bewerten
- Teilen
- Produkt teilen
- Produkterinnerung
- Produkterinnerung
This book provides an introduction to the field of biomarkers, how they have been and can be used, and how different approaches can be used to identify, characterize, and monitor biomarkers. The book has chapters on topics including HIV, Cancer, Parkinson's, vascular injury, environmental exposure. A following section discusses the technologies (diagnostics and assays) to detect biomarkers and authors have emphasized the preclinical and clinical manifestation of the injury/disease process.
Andere Kunden interessierten sich auch für
- Drug Development205,99 €
- Pharmaceutical Toxicology in Practice144,99 €
- Evaluation of Drug Candidates for Preclinical Development196,99 €
- Predictive Approaches in Drug Discovery and Development177,99 €
- Shiqi PengPharmaceutical Bioassays189,99 €
- Blood-Brain Barrier in Drug Discovery170,99 €
- John L. LaMattinaDrug Truths31,99 €
-
-
-
This book provides an introduction to the field of biomarkers, how they have been and can be used, and how different approaches can be used to identify, characterize, and monitor biomarkers. The book has chapters on topics including HIV, Cancer, Parkinson's, vascular injury, environmental exposure. A following section discusses the technologies (diagnostics and assays) to detect biomarkers and authors have emphasized the preclinical and clinical manifestation of the injury/disease process.
Produktdetails
- Produktdetails
- Verlag: John Wiley & Sons / Wiley
- Seitenzahl: 632
- Erscheinungstermin: 5. Oktober 2010
- Englisch
- Abmessung: 244mm x 167mm x 37mm
- Gewicht: 1167g
- ISBN-13: 9780470452240
- ISBN-10: 0470452242
- Artikelnr.: 30882420
- Verlag: John Wiley & Sons / Wiley
- Seitenzahl: 632
- Erscheinungstermin: 5. Oktober 2010
- Englisch
- Abmessung: 244mm x 167mm x 37mm
- Gewicht: 1167g
- ISBN-13: 9780470452240
- ISBN-10: 0470452242
- Artikelnr.: 30882420
VISHAL S. VAIDYA, PhD, is an Assistant Professor of Medicine at Harvard Medical School in the Renal Division of Brigham and Women's Hospital. He directs the Laboratory of Kidney Toxicology and Regeneration with a research emphasis on discovery and evaluation of biomarkers and biosensors for early detection of kidney injury and investigates the molecular mechanisms of kidney tissue repair. Dr. Vaidya has authored more than thirty-five original research articles and twelve chapters and reviews. He serves as a councilor for the northeast chapter of the Society of Toxicology and is an elected member of Harvard School of Public Health's Center for Environmental Health. He is the recipient of the Pathway to Independence grant by the National Institute of Environmental Health Sciences. JOSEPH V. BONVENTRE, MD, PhD, is the Samuel A. Levine Professor of Medicine at Harvard Medical School. He is also Chief of the Renal Division and Director of the Biomedical Engineering Division of Brigham and Women's Hospital and is President-elect of the American Society of Nephrology. He has authored more than 250 original papers and 120 chapters and reviews. His research focuses primarily on the study of kidney injury and repair and signal transduction, with special emphasis on the role of inflammation, biomarkers, and stem cells. Bonventre has received a MERIT award from the National Institute of Diabetes and Digestive and Kidney Diseases.
Preface. Contributors. 1 Biomarkers: An Evolutionary Perspective (Michael
Ferguson and Vishal Vaidya). SECTION I: TOOLS FOR BIOMARKER DISCOVERY. 2
Genomics (Weida Tong and Donna L. Mendrick). 3 Proteomics for Biomarker
Discovery (Timothy D. Veenstra). 4 Metabolic Profiling for Biomarker
Discovery (Hector C. Keun). 5 The Bittersweet Promise of Glycobiology
(Padmaparna Chaudhuri, Rania Harfouche, and Shiladitya Sengupta). SECTION
II: BIOMARKERS OF INJURY/DISEASE. 6 Biomarkers of Alzheimer's and
Parkinson's Disease (Walter Maetzler and Daniela Berg). 7 Biomarkers of
Cardiac Injury (Anthony S. McLean and Stephen J. Huang). 8 Lung Injury
Biomarkers (Urmila P. Kodavanti). 9 Translational Biomarkers of Acute
Drug-Induced Liver Injury: The Current State, Gaps and Future Opportunities
(Josef Ozer, William Reagan, Sheli Schomaker, Joe Palandra, Mike Baratta
and Shashi Ramaiah). 10 Biomarkers of Acute Kidney Injury (Frank Dieterle
and Frank Sistare). 11 In Search of Biomarkers for Drug-Induced Vascular
Injury (James R. Turk). 12 Biomarkers of Immunotoxicity (Rodney R.
Dietert). 13 Biomarkers in Obstetric Medicine (Manish Maski, Sarosh Rana
and S. Ananth Karumanchi. 14 Biomarkers in Cancer (Roopali Roy, Christine
M. Coticchia, Jiang Yang and Marsha A. Moses). 15 Biomarkers of HIV (Lewis
Kaufman and Michael J Ross). 16 Biomarkers of In Vitro Drug-Induced
Mitochondrial Dysfunction (James A. Dykens and Yvonne Will). SECTION III:
TECHNOLOGY FOR BIOMARKER DETECTION. 17 Immunoassay-Based Technologies for
the Measurement of Biological Materials Used for Biomarkers Discovery and
Translational Research (Vincent Ricchiuti). 18 Nanoscale Techniques for
Biomarker Quantification (Madhukar Varshney, and Harold G. Craighead). 19
Immunodiagnostics with a Focus on Lateral Flow Point-of-Care Devices (Roy
R. Mondesire, Glen M. Ford, Hannie F. Ford, and Stephen C. Mefferd).
SECTION IV: HOT TOPICS IN BIOMARKER RESEARCH. 20 Biomarkers for
Environmental Exposure (Jane E. Gallagher, Elaine A. Cohen Hubal and
Stephen W. Edwards). 21 Clinical Study Design in Biomarker Research (Orfeas
Liangos and Bertrand L. Jaber). 22 Statistical Issues in Biomarker Research
(Daniel Holder and Matthew Schipper). 23 Regulatory Perspective for
Biomarker Qualification from U.S. FDA (Federico Goodsaid). 24 The European
Medicines Agency Approach (Marisa Papaluca Amati and Spiros Vamvakas).
Index.
Ferguson and Vishal Vaidya). SECTION I: TOOLS FOR BIOMARKER DISCOVERY. 2
Genomics (Weida Tong and Donna L. Mendrick). 3 Proteomics for Biomarker
Discovery (Timothy D. Veenstra). 4 Metabolic Profiling for Biomarker
Discovery (Hector C. Keun). 5 The Bittersweet Promise of Glycobiology
(Padmaparna Chaudhuri, Rania Harfouche, and Shiladitya Sengupta). SECTION
II: BIOMARKERS OF INJURY/DISEASE. 6 Biomarkers of Alzheimer's and
Parkinson's Disease (Walter Maetzler and Daniela Berg). 7 Biomarkers of
Cardiac Injury (Anthony S. McLean and Stephen J. Huang). 8 Lung Injury
Biomarkers (Urmila P. Kodavanti). 9 Translational Biomarkers of Acute
Drug-Induced Liver Injury: The Current State, Gaps and Future Opportunities
(Josef Ozer, William Reagan, Sheli Schomaker, Joe Palandra, Mike Baratta
and Shashi Ramaiah). 10 Biomarkers of Acute Kidney Injury (Frank Dieterle
and Frank Sistare). 11 In Search of Biomarkers for Drug-Induced Vascular
Injury (James R. Turk). 12 Biomarkers of Immunotoxicity (Rodney R.
Dietert). 13 Biomarkers in Obstetric Medicine (Manish Maski, Sarosh Rana
and S. Ananth Karumanchi. 14 Biomarkers in Cancer (Roopali Roy, Christine
M. Coticchia, Jiang Yang and Marsha A. Moses). 15 Biomarkers of HIV (Lewis
Kaufman and Michael J Ross). 16 Biomarkers of In Vitro Drug-Induced
Mitochondrial Dysfunction (James A. Dykens and Yvonne Will). SECTION III:
TECHNOLOGY FOR BIOMARKER DETECTION. 17 Immunoassay-Based Technologies for
the Measurement of Biological Materials Used for Biomarkers Discovery and
Translational Research (Vincent Ricchiuti). 18 Nanoscale Techniques for
Biomarker Quantification (Madhukar Varshney, and Harold G. Craighead). 19
Immunodiagnostics with a Focus on Lateral Flow Point-of-Care Devices (Roy
R. Mondesire, Glen M. Ford, Hannie F. Ford, and Stephen C. Mefferd).
SECTION IV: HOT TOPICS IN BIOMARKER RESEARCH. 20 Biomarkers for
Environmental Exposure (Jane E. Gallagher, Elaine A. Cohen Hubal and
Stephen W. Edwards). 21 Clinical Study Design in Biomarker Research (Orfeas
Liangos and Bertrand L. Jaber). 22 Statistical Issues in Biomarker Research
(Daniel Holder and Matthew Schipper). 23 Regulatory Perspective for
Biomarker Qualification from U.S. FDA (Federico Goodsaid). 24 The European
Medicines Agency Approach (Marisa Papaluca Amati and Spiros Vamvakas).
Index.
Preface. Contributors. 1 Biomarkers: An Evolutionary Perspective (Michael
Ferguson and Vishal Vaidya). SECTION I: TOOLS FOR BIOMARKER DISCOVERY. 2
Genomics (Weida Tong and Donna L. Mendrick). 3 Proteomics for Biomarker
Discovery (Timothy D. Veenstra). 4 Metabolic Profiling for Biomarker
Discovery (Hector C. Keun). 5 The Bittersweet Promise of Glycobiology
(Padmaparna Chaudhuri, Rania Harfouche, and Shiladitya Sengupta). SECTION
II: BIOMARKERS OF INJURY/DISEASE. 6 Biomarkers of Alzheimer's and
Parkinson's Disease (Walter Maetzler and Daniela Berg). 7 Biomarkers of
Cardiac Injury (Anthony S. McLean and Stephen J. Huang). 8 Lung Injury
Biomarkers (Urmila P. Kodavanti). 9 Translational Biomarkers of Acute
Drug-Induced Liver Injury: The Current State, Gaps and Future Opportunities
(Josef Ozer, William Reagan, Sheli Schomaker, Joe Palandra, Mike Baratta
and Shashi Ramaiah). 10 Biomarkers of Acute Kidney Injury (Frank Dieterle
and Frank Sistare). 11 In Search of Biomarkers for Drug-Induced Vascular
Injury (James R. Turk). 12 Biomarkers of Immunotoxicity (Rodney R.
Dietert). 13 Biomarkers in Obstetric Medicine (Manish Maski, Sarosh Rana
and S. Ananth Karumanchi. 14 Biomarkers in Cancer (Roopali Roy, Christine
M. Coticchia, Jiang Yang and Marsha A. Moses). 15 Biomarkers of HIV (Lewis
Kaufman and Michael J Ross). 16 Biomarkers of In Vitro Drug-Induced
Mitochondrial Dysfunction (James A. Dykens and Yvonne Will). SECTION III:
TECHNOLOGY FOR BIOMARKER DETECTION. 17 Immunoassay-Based Technologies for
the Measurement of Biological Materials Used for Biomarkers Discovery and
Translational Research (Vincent Ricchiuti). 18 Nanoscale Techniques for
Biomarker Quantification (Madhukar Varshney, and Harold G. Craighead). 19
Immunodiagnostics with a Focus on Lateral Flow Point-of-Care Devices (Roy
R. Mondesire, Glen M. Ford, Hannie F. Ford, and Stephen C. Mefferd).
SECTION IV: HOT TOPICS IN BIOMARKER RESEARCH. 20 Biomarkers for
Environmental Exposure (Jane E. Gallagher, Elaine A. Cohen Hubal and
Stephen W. Edwards). 21 Clinical Study Design in Biomarker Research (Orfeas
Liangos and Bertrand L. Jaber). 22 Statistical Issues in Biomarker Research
(Daniel Holder and Matthew Schipper). 23 Regulatory Perspective for
Biomarker Qualification from U.S. FDA (Federico Goodsaid). 24 The European
Medicines Agency Approach (Marisa Papaluca Amati and Spiros Vamvakas).
Index.
Ferguson and Vishal Vaidya). SECTION I: TOOLS FOR BIOMARKER DISCOVERY. 2
Genomics (Weida Tong and Donna L. Mendrick). 3 Proteomics for Biomarker
Discovery (Timothy D. Veenstra). 4 Metabolic Profiling for Biomarker
Discovery (Hector C. Keun). 5 The Bittersweet Promise of Glycobiology
(Padmaparna Chaudhuri, Rania Harfouche, and Shiladitya Sengupta). SECTION
II: BIOMARKERS OF INJURY/DISEASE. 6 Biomarkers of Alzheimer's and
Parkinson's Disease (Walter Maetzler and Daniela Berg). 7 Biomarkers of
Cardiac Injury (Anthony S. McLean and Stephen J. Huang). 8 Lung Injury
Biomarkers (Urmila P. Kodavanti). 9 Translational Biomarkers of Acute
Drug-Induced Liver Injury: The Current State, Gaps and Future Opportunities
(Josef Ozer, William Reagan, Sheli Schomaker, Joe Palandra, Mike Baratta
and Shashi Ramaiah). 10 Biomarkers of Acute Kidney Injury (Frank Dieterle
and Frank Sistare). 11 In Search of Biomarkers for Drug-Induced Vascular
Injury (James R. Turk). 12 Biomarkers of Immunotoxicity (Rodney R.
Dietert). 13 Biomarkers in Obstetric Medicine (Manish Maski, Sarosh Rana
and S. Ananth Karumanchi. 14 Biomarkers in Cancer (Roopali Roy, Christine
M. Coticchia, Jiang Yang and Marsha A. Moses). 15 Biomarkers of HIV (Lewis
Kaufman and Michael J Ross). 16 Biomarkers of In Vitro Drug-Induced
Mitochondrial Dysfunction (James A. Dykens and Yvonne Will). SECTION III:
TECHNOLOGY FOR BIOMARKER DETECTION. 17 Immunoassay-Based Technologies for
the Measurement of Biological Materials Used for Biomarkers Discovery and
Translational Research (Vincent Ricchiuti). 18 Nanoscale Techniques for
Biomarker Quantification (Madhukar Varshney, and Harold G. Craighead). 19
Immunodiagnostics with a Focus on Lateral Flow Point-of-Care Devices (Roy
R. Mondesire, Glen M. Ford, Hannie F. Ford, and Stephen C. Mefferd).
SECTION IV: HOT TOPICS IN BIOMARKER RESEARCH. 20 Biomarkers for
Environmental Exposure (Jane E. Gallagher, Elaine A. Cohen Hubal and
Stephen W. Edwards). 21 Clinical Study Design in Biomarker Research (Orfeas
Liangos and Bertrand L. Jaber). 22 Statistical Issues in Biomarker Research
(Daniel Holder and Matthew Schipper). 23 Regulatory Perspective for
Biomarker Qualification from U.S. FDA (Federico Goodsaid). 24 The European
Medicines Agency Approach (Marisa Papaluca Amati and Spiros Vamvakas).
Index.