Periodontal disease, characterized by the destruction of the supporting structures of the teeth, remains a prevalent and challenging condition to manage. Traditional treatments often fall short in achieving complete regeneration of periodontal tissues, highlighting the need for advanced therapeutic approaches. Biomaterials have emerged as a pivotal element in periodontal regeneration, offering innovative solutions to restore the alveolar bone, periodontal ligament, and cementum. This abstract provides an overview of the key concepts, materials, and future directions in the field of biomaterials used for periodontal regeneration.The development and application of biomaterials are driven by their ability to provide a conducive environment for tissue growth and healing. These materials can be broadly categorized into natural, synthetic, and composite biomaterials. Biomaterials hold great promise in advancing periodontal regeneration, offering innovative solutions to restore damaged periodontal tissues. Continued research and development in this field are essential to overcome current limitations and achieve consistent, long-term clinical success.