Biomedical Nanosensors

Herausgeber: Irudayaraj, Joseph M

• Gebundenes Buch

Produktbeschreibung

This book draws together recent data on both cytoplasmic and flagellar dyneins and the proteins they interact with, to give the reader a clear picture of what is currently known about the structure and mechanics of these remarkable macro-molecular machines. Each chapter is written by active researchers, with a focus on currently used biophysical, biochemical, and cell biological methods. In addition to comprehensive coverage of structural information gained by electron microscopy, electron cryo-tomography, X-ray crystallography, and nuclear magnetic resonance, this book provides detailed descriptions of mechanistic experiments by single-molecule nanometry.

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Produktdetails

• Verlag: Taylor & Francis Ltd (Sales)
• Seitenzahl: 410
• Erscheinungstermin: 21. November 2012
• Englisch
• Abmessung: 254mm x 178mm x 24mm
• Gewicht: 930g
• ISBN-13: 9789814303033
• ISBN-10: 9814303038
• Artikelnr.: 34797803

Autorenporträt

Joseph M. Irudayaraj

Inhaltsangabe

Dyneins: Ancient Protein Complexes Gradually Reveal Their Secrets. Two
Decades of Cytoplasmic Dynein: From Fast to Forceful. Functional Analysis
of the Dynein Motor Domain. Structural Studies on the Dynein Heavy Chain.
Structural Analysis of Microtubule-Bound Dynein. The Dynein Stalk: Atomic
Structure and Roles in the Mechanism of the Dynein Motor. Enzymatic and
Motile Properties of Native Dynein Molecules. Motile Properties of
Cytoplasmic Dynein. Motile Properties of Inner Arm Dynein. Dynein Motility
in Cilia and Flagella. 3D Structures of Axonemes. Functional Diversity of
Axonemal Dyneins. Assembly and Regulation of Dynein Light Chains.
Regulatory Subunits of Axonemal Dynein. The Role of Dynein in Yeast Nuclear
Segregation.