Biomineralization Sourcebook
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This handbook provides a comprehensive account of materials science approaches to characterization of biominerals and biomimetic model systems. It covers state-of-the-art in the characterization of atomic and molecular structure, including the latest in diffraction, scattering, and spectroscopy, in addition to methods for imaging morphology and interfaces. It also looks at computational approaches and probes for examining energetics and forces in assembly. The final section focuses on mechanical function and measurement methodology as well as studies of live cells and whole organ.

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Produktbeschreibung
This handbook provides a comprehensive account of materials science approaches to characterization of biominerals and biomimetic model systems. It covers state-of-the-art in the characterization of atomic and molecular structure, including the latest in diffraction, scattering, and spectroscopy, in addition to methods for imaging morphology and interfaces. It also looks at computational approaches and probes for examining energetics and forces in assembly. The final section focuses on mechanical function and measurement methodology as well as studies of live cells and whole organ.
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Autorenporträt
Elaine DiMasi is a physicist and synchrotron x-ray scattering expert, and has made her career at Brookhaven National Laboratory since 1996. Research for her PhD (University of Michigan, Ann Arbor) and postdoctoral appointment (BNL) focused on structure and electronic properties in metallic condensed matter systems. Since 1999 she has investigated numerous aspects of Biomineralization including: mineralization at Langmuir films, assembly and mineralization of extracellular matrix proteins, structures of organics assembled on mineral surfaces, and microbeam diffraction mapping of mineral-organic composites and biological minerals. More recent areas of interest include lipid-mineral interactions and soft X-ray microspectroscopy. DiMasi currently is engaged in building a state of the art synchrotron x-ray scattering facility at the National Synchrotorn Light Source II, dedicated to soft- and bio-materials, specializing in aqueous interfaces, providing the capabilities to measure hierarchical structures of biominerals for a wide range of length scales and in realistic material environments. Laurie B. Gower is an Associate Professor in the Department of Materials Science & Engineering, and supervisor of the Biomimetics Laboratory at the University of Florida. Her Master's degree from University of Utah was in the area of Bioengineering (1990), and doctoral degree from UMASS at Amherst was in the area of Polymer Science & Engineering (1997). In the latter case, her dissertation was focused on biomineralization, making use of model systems to examine the interactions between polypeptides and crystal growth, and correlating features observed in the in vitro systems to those observed in biominerals. Most of the research in her academic career has continued along these lines of examining potential mechanisms involved in biomineralization. She discovered a novel crystallization process that relies on a polymer-induced liquid-precursor (PILP) phase, and was one of the first to suggest that biominerals might be formed from a hydrated amorphous precursor. She has built a line of evidence to suggest that this polymer-directed crystallization process may play a fundamental role in both calcium carbonate (marine exoskeletons) and calcium phosphate (bones and teeth) biomineralization, as well as calcium oxalate precipitation in kidney stones.