Douglas Barrick (Johns Hopkins University, Baltimore, Maryland, USA

Biomolecular Thermodynamics

From Theory to Application

• Broschiertes Buch

Produktbeschreibung

This book introduces the concepts and practical tools necessary to understand the behavior of biological macromolecules at a quantitative level, going beyond theory to explain in detail how the equations are applied to the analysis of experimental measurements. An emphasis on real-world applications is a continued throughout the book.

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Produktdetails

• Foundations of Biochemistry and Biophysics
• Verlag: Taylor & Francis Inc
• Seitenzahl: 524
• Erscheinungstermin: 14. September 2017
• Englisch
• Abmessung: 279mm x 218mm x 27mm
• Gewicht: 1524g
• ISBN-13: 9781439800195
• ISBN-10: 1439800197
• Artikelnr.: 24907408

Autorenporträt

Douglas E. Barrick is a professor in the Department of Biophysics at Johns Hopkins University. He earned a Ph.D. in biochemistry from Stanford University (1993) and Ph.D. in biophysics and structural biology from the University of Oregon (1996). He has been honored as recipient of the Beckman Young Investigator award, the Helen Hay Whitney Postdoctoral fellowship, and Howard Hughes Medical Institute Predoctoral Fellowship. He has been an editorial board member of the journals Protein Science and Biophysical Journal, and has been an organizer of the Gibbs Conference on Biothermodynamics. Research in his lab focuses on the study of protein evolution, folding, and assembly.

Inhaltsangabe

Series Preface
Preface
Acknowledgments
Note to Instructors
Author
Chapter 1 Probabilities and Statistics in Chemical and Biothermodynamics
Chapter 2 Mathematical Tools in Thermodynamics
Chapter 3 The Framework of Thermodynamics and the First Law
Chapter 4 The Second Law and Entropy
Chapter 5 Free Energy as a Potential for the Laboratory and for Biology
Chapter 6 Using Chemical Potentials to Describe Phase Transitions
Chapter 7 The Concentration Dependence of Chemical Potential, Mixing, and
Reactions
Chapter 8 Conformational Equilibrium
Chapter 9 Statistical Thermodynamics and the Ensemble Method
Chapter 10 Ensembles That Interact with Their Surroundings
Chapter 11 Partition Functions for Single Molecules and Chemical Reactions
Chapter 12 The Helix-Coil Transition
Chapter 13 Ligand Binding Equilibria from a Macroscopic Perspective
Chapter 14 Ligand Binding Equilibria from a Microscopic Perspective
Appendix: How to Use Mathematica 485
Bibliography
Index