Biopathology of Congenital Hydrocephalus and Arnold Chiari Malformation - Castejón, Orlando J.
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This book provides a pathological alteration of neurons and glial cells in congenital hydrocephalus and Arnold Chiari Malformation examined by means of transmission electron microscopy using cortical biopsis of infant patients taken during neurosurgical treatment and immediately fixed in the surgical room to avoid delayed fixation artifacts and postmortem changes. We have described the pathological changes of nerve cell organelles, immature synapses, synaptic plasticity and synaptic degeneration, neuroglial cells and extracellular space. We have systematically related the submicroscopic…mehr

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Produktbeschreibung
This book provides a pathological alteration of neurons and glial cells in congenital hydrocephalus and Arnold Chiari Malformation examined by means of transmission electron microscopy using cortical biopsis of infant patients taken during neurosurgical treatment and immediately fixed in the surgical room to avoid delayed fixation artifacts and postmortem changes. We have described the pathological changes of nerve cell organelles, immature synapses, synaptic plasticity and synaptic degeneration, neuroglial cells and extracellular space. We have systematically related the submicroscopic findings and the pathogenic and pathophysiological mechanisms involved in hydrocephalic edema and intracranial hypertension.
Autorenporträt
El Dr. Orlando J. Castejón, MD, DMSci, DHC es neurocientífico, profesor emérito y director fundador del Instituto de Investigación Biológica. Facultad de Medicina. Universidad del Zulia en Venezuela. Autor de 200 artículos de investigación y revisión y 12 libros publicados en revistas internacionales sobre microscopía electrónica de la corteza cerebelosa y edema cerebral humano