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Designed as a basic reference for researchers in a wide variety of disciplines, this book discusses plant transformation techniques, the generation of transgenic plants, and the engineering of plant viruses to produce vaccine proteins or peptides. It addresses the basis of mucosal immunity using plant-based oral vaccines, organelle targeting for vaccine production, and the role of glycosylation in plant-made mammalian proteins. It also considers vaccine production in entire crops or in large batch cell suspension cultures as well as the development of clinical trials. The book concludes with a risk analysis and discussion of future applications.…mehr

Produktbeschreibung
Designed as a basic reference for researchers in a wide variety of disciplines, this book discusses plant transformation techniques, the generation of transgenic plants, and the engineering of plant viruses to produce vaccine proteins or peptides. It addresses the basis of mucosal immunity using plant-based oral vaccines, organelle targeting for vaccine production, and the role of glycosylation in plant-made mammalian proteins. It also considers vaccine production in entire crops or in large batch cell suspension cultures as well as the development of clinical trials. The book concludes with a risk analysis and discussion of future applications.
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Autorenporträt
Kathleen Laura Hefferon achieved her Ph.D. at the University of Toronto. She most recently held the title of Director of Operations of the Human Metabolic Research Unit in the Division of Nutritional Sciences at Cornell University. She also acts as a science writer for the Center for Hepatitis C Research at Rockefeller University in New York City and as an expert selector for the Infection and Immunity Division of the Medical Research Council, in London.