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The aim of our research project is to highlight the medical application of physics, although we as Pharmacologist remain often focused on the value of pedications to resolve any disease, however we noticed some complicated medical problems, such as antibiotic resistance where we cannot find any responsive chemical therapy therefore we referred to the history of bioresonance therapy. However, we were also concerned to report the medical value by following some patients who were treated, and to analyze the mechanism in which this therapy is effective, and for which diseases. And we also hope that this established device for targeting bacteria, viruses can hold a hope for patients who are diagnosed with Coronavirus, there is a proof of principle for that hypothesis since the scientist Rife has invented this therapy by interference destruction wave, which could destroy specifically this bacteria upon its frequency wave without possible side effects to normal tissue, so we aim to start a clinical trial for the COVID-19 disease too and we will present the concept of Telemedicine where we can treat patients whom are in the countryside where all the tests can be transferred wireless.