This book emphasizes the importance of microbial physiology, biochemistry, genetics, and evolution in the study of biosynthesis. It takes into account the considerable advances made in the field in the last twenty years by the introduction of gene cloning and sequencing and by the exponential development of physical methods such as X-ray crystallography of proteins.
This book emphasizes the importance of microbial physiology, biochemistry, genetics, and evolution in the study of biosynthesis. It takes into account the considerable advances made in the field in the last twenty years by the introduction of gene cloning and sequencing and by the exponential development of physical methods such as X-ray crystallography of proteins.
Introduction; Bacterial growth; Cellular permeability; Allosteric enzymes; Enzyme induction in catabolic systems; Negative regulation; Transcription RNA polymerase; Attenuation; Enzyme repression in anabolic systems; How to study biosynthetic pathways; Biosynthesis of lipids; The biological fixation of nitrogen; Biosynthesis of the aspartic acid family of amino acids; Regulation of the biosynthesis of the amino acids of the aspartic acid family in Enterobacteriaceae; The regulation of the amino acids of the aspartate family in other microorganisms; Biosynthesis of the amino acids of the glutamic acid family and its regulation; Biosynthesis of amino acids derived from phosphoglyceric acid and pyruvic acid; Biosynthesis of aromatic amino acids and its regulation; Regulation of histidine biosynthesis at the genetic level; The biosynthesis of nucleotides; The biosynthesis of deoxyribonucleotides; Biosynthesis of some water-soluble vitamins and of their coenzyme forms; Biosynthesis of
Introduction; Bacterial growth; Cellular permeability; Allosteric enzymes; Enzyme induction in catabolic systems; Negative regulation; Transcription RNA polymerase; Attenuation; Enzyme repression in anabolic systems; How to study biosynthetic pathways; Biosynthesis of lipids; The biological fixation of nitrogen; Biosynthesis of the aspartic acid family of amino acids; Regulation of the biosynthesis of the amino acids of the aspartic acid family in Enterobacteriaceae; The regulation of the amino acids of the aspartate family in other microorganisms; Biosynthesis of the amino acids of the glutamic acid family and its regulation; Biosynthesis of amino acids derived from phosphoglyceric acid and pyruvic acid; Biosynthesis of aromatic amino acids and its regulation; Regulation of histidine biosynthesis at the genetic level; The biosynthesis of nucleotides; The biosynthesis of deoxyribonucleotides; Biosynthesis of some water-soluble vitamins and of their coenzyme forms; Biosynthesis of
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