Textiles play a vital role in the manufacture of various medical devices, including the replacement of diseased, injured or non-functioning organs within the body. Biotextiles as medical implants provides an invaluable single source of information on the main types of textile materials and products used for medical implants. The first part of the book focuses on polymers, fibers and textile technologies, and these chapters discuss the manufacture, sterilization, properties and types of biotextiles used for medical applications, including nanofibers, resorbable polymers and shaped biotextiles.…mehr
Textiles play a vital role in the manufacture of various medical devices, including the replacement of diseased, injured or non-functioning organs within the body. Biotextiles as medical implants provides an invaluable single source of information on the main types of textile materials and products used for medical implants. The first part of the book focuses on polymers, fibers and textile technologies, and these chapters discuss the manufacture, sterilization, properties and types of biotextiles used for medical applications, including nanofibers, resorbable polymers and shaped biotextiles. The chapters in part two provide a comprehensive discussion of a range of different clinical applications of biotextiles, including surgical sutures, arterial prostheses, stent grafts, percutaneous heart valves and drug delivery systems.This book provides a concise review of the technologies, properties and types of biotextiles used as medical devices. In addition, it addresses the biological dimension of how to design devices for different clinical applications, providing an invaluable reference for biomedical engineers of medical textiles, quality control and risk assessment specialists, as well as managers of regulatory affairs. The subject matter will also be of interest to professionals within the healthcare system including surgeons, nurses, therapists, sourcing and purchasing agents, researchers and students in different disciplines.
Martin W. King is Professor of Biotextiles and Textile Technology, North Carolina State University, Raleigh, USA, and Chaired Professor of Medical Textiles, Donghua University, Shanghai, China
Dr Bhupender S. Gupta is Professor of Textile Engineering, Chemistry and Science at North Carolina State University, USA. Professor Gupta is internationally renowned for his research in textile science.
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Woodhead Publishing Series in Textiles
Preface
Introduction
Part I: Technologies
Chapter 1: Manufacture, types and properties of biotextiles for medical applications
Abstract:
1.1 Introduction
1.2 Fiber structure
1.3 Formation of synthetic fibers
1.4 Processing of short (staple) and continuous (filament) fibers
1.5 Understanding structure in fibers
1.6 Fibrous materials used in medicine
1.7 Key fiber properties
1.8 Textile assemblies and their characteristics
1.9 Conclusion
1.10 Sources of further information and advice
1.11 Acknowledgments
Chapter 2: Nanofiber structures for medical biotextiles
Abstract:
2.1 Introduction
2.2 Techniques for producing nanofibers
2.3 The electrospinning process
2.4 Using electrospun poly(s-caprolactone) (PCL) fibers as scaffolds for tissue engineering
2.5 Co-axial bicomponent nanofibers and their production
2.6 Case study: collagen/PCL bicomponent nanofiber scaffolds for engineering bone tissues
2.7 In vivo case study: engineering of blood vessels
2.8 Miscellaneous applications of co-axial nanofiber structures
2.9 Conclusion
Chapter 3: Resorbable polymers for medical applications
Abstract:
3.1 Introduction
3.2 Polymer degradation
3.3 Mechanical properties of existing resorbable polymers
3.4 Mechano-active tissue engineering
3.5 Elastomeric properties of fiber-forming copolymers
3.6 Elastomeric resorbable polymers for vascular tissue engineering
3.7 Conclusion and future trends
Chapter 4: Shaped biotextiles for medical implants
Abstract:
4.1 Introduction
4.2 Vascular grafts: key developments
4.3 Weaving, knitting and ePTFE technologies for producing tubular structures
4.4 Improving surface properties: velour construction
4.5 Multilimbed grafts
4.6 Heat setting for a more resilient crimped circular configuration
4.7 Grafts with taper and varying diameter
4.8 Tubular structures for other devices: ligaments, hernia and prolapsed repair meshes
4.9 Three-dimensional textile structures
4.10 Performance requirements of implants in the body
4.11 Conclusion
4.12 Acknowledgements
Chapter 5: Surface modification of biotextiles for medical applications
Abstract:
5.1 Introduction
5.2 Nano-coatings
5.3 Preparation of textile surfaces
5.4 Plasma technologies for surface treatment
5.5 Measuring surface properties of textiles: SEM and XPS
5.6 Testing antimicrobial coatings
5.7 Applications of surface treatments in medical textiles
5.8 Future trends
5.9 Sources of further information and advice
Chapter 6: Sterilization techniques for biotextiles for medical applications
Abstract:
6.1 Introduction
6.2 Bioburden and principles of sterilization
6.3 Traditional sterilization: advantages and disadvantages
6.4 Emerging and less traditional sterilization methods
6.5 Radiochemical sterilization (RCS)
6.6 Application of RCS technology
6.7 Conclusion and future trends
Chapter 7: Regulation of biotextiles for medical use
Abstract:
7.1 Introduction
7.2 US regulation of biotextiles
7.3 European Union regulation of biotextiles
7.4 Quality standards for biotextiles
7.5 The role of quality standards in the development of biotextiles
7.6 Safety issues with 'me-too' products with new intended uses
7.7 Dealing with cutting-edge technology
7.8 Conclusion
Chapter 8: Retrieval studies for medical biotextiles
Abstract:
8.1 Introduction
8.2 Standards and animal models for implant retrieval studies
Chapter 1: Manufacture, types and properties of biotextiles for medical applications
Abstract:
1.1 Introduction
1.2 Fiber structure
1.3 Formation of synthetic fibers
1.4 Processing of short (staple) and continuous (filament) fibers
1.5 Understanding structure in fibers
1.6 Fibrous materials used in medicine
1.7 Key fiber properties
1.8 Textile assemblies and their characteristics
1.9 Conclusion
1.10 Sources of further information and advice
1.11 Acknowledgments
Chapter 2: Nanofiber structures for medical biotextiles
Abstract:
2.1 Introduction
2.2 Techniques for producing nanofibers
2.3 The electrospinning process
2.4 Using electrospun poly(s-caprolactone) (PCL) fibers as scaffolds for tissue engineering
2.5 Co-axial bicomponent nanofibers and their production
2.6 Case study: collagen/PCL bicomponent nanofiber scaffolds for engineering bone tissues
2.7 In vivo case study: engineering of blood vessels
2.8 Miscellaneous applications of co-axial nanofiber structures
2.9 Conclusion
Chapter 3: Resorbable polymers for medical applications
Abstract:
3.1 Introduction
3.2 Polymer degradation
3.3 Mechanical properties of existing resorbable polymers
3.4 Mechano-active tissue engineering
3.5 Elastomeric properties of fiber-forming copolymers
3.6 Elastomeric resorbable polymers for vascular tissue engineering
3.7 Conclusion and future trends
Chapter 4: Shaped biotextiles for medical implants
Abstract:
4.1 Introduction
4.2 Vascular grafts: key developments
4.3 Weaving, knitting and ePTFE technologies for producing tubular structures
4.4 Improving surface properties: velour construction
4.5 Multilimbed grafts
4.6 Heat setting for a more resilient crimped circular configuration
4.7 Grafts with taper and varying diameter
4.8 Tubular structures for other devices: ligaments, hernia and prolapsed repair meshes
4.9 Three-dimensional textile structures
4.10 Performance requirements of implants in the body
4.11 Conclusion
4.12 Acknowledgements
Chapter 5: Surface modification of biotextiles for medical applications
Abstract:
5.1 Introduction
5.2 Nano-coatings
5.3 Preparation of textile surfaces
5.4 Plasma technologies for surface treatment
5.5 Measuring surface properties of textiles: SEM and XPS
5.6 Testing antimicrobial coatings
5.7 Applications of surface treatments in medical textiles
5.8 Future trends
5.9 Sources of further information and advice
Chapter 6: Sterilization techniques for biotextiles for medical applications
Abstract:
6.1 Introduction
6.2 Bioburden and principles of sterilization
6.3 Traditional sterilization: advantages and disadvantages
6.4 Emerging and less traditional sterilization methods
6.5 Radiochemical sterilization (RCS)
6.6 Application of RCS technology
6.7 Conclusion and future trends
Chapter 7: Regulation of biotextiles for medical use
Abstract:
7.1 Introduction
7.2 US regulation of biotextiles
7.3 European Union regulation of biotextiles
7.4 Quality standards for biotextiles
7.5 The role of quality standards in the development of biotextiles
7.6 Safety issues with 'me-too' products with new intended uses
7.7 Dealing with cutting-edge technology
7.8 Conclusion
Chapter 8: Retrieval studies for medical biotextiles
Abstract:
8.1 Introduction
8.2 Standards and animal models for implant retrieval studies
8.3 Testing retriev
Rezensionen
"Regenerative Medicine: Biotextiles as Medical Implants. M W King, B S Gupta, and R Guidoin, Eds. Woodhead Publishing. Philadelphia, PA. 2013. 738 pages. $330.00." --Journal of Controlled Release 183, 2014
"A new book from Woodhead Publishing in association with the Textile Institute provides an invaluable source of information on the main types of textile materials and products used for medical implants." --Technical-Textiles.net, February 2014
"Some from medicine and some from textiles, scientists present a textbook for an undergraduate textiles course on textile devices that can be implanted for medical purposes. Covering first technologies then applications, they explore such topics as resorbable polymers for medical applications, surface modification, sterilization techniques, retrieval studies for medical biotextiles, types and properties of surgical sutures, barbed suture technology,." --ProtoView.com, February 2014
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