E. Tsuchida

Blood Substitutes, Present and Future Perspectives

• Gebundenes Buch

Produktbeschreibung

This book contains the selected papers presented at the seventh International Symposium on Blood Substitutes (7th ISBS) held at the International Conference Center of Waseda University in Tokyo on 7-10 September 1997. In keeping with the scientific design of the 7th ISBS Symposium, chapters have been carefully selected and organized to showcase the advancements in recent research. This book includes up-to-date clinical results of leading companies which are manufacturing hemoglobin-based or fluorocarbon-based blood substitutes, and covers issues of hemoglobin toxicity and side effects such as vasoconstriction in more detail using carefully designed in vivo and ex vivo techniques. This book is also a collection of various new types of red cell substitutes such as recombinant Hbs, recombinant albumine-lipidheme complex, modified red blood cells, and perfluorochemicals using material science and molecular engineering.

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Produktdetails

• Verlag: Elsevier Science
• Seitenzahl: 390
• Erscheinungstermin: 14. Januar 1999
• Englisch
• Abmessung: 245mm x 175mm x 25mm
• Gewicht: 890g
• ISBN-13: 9780444205247
• ISBN-10: 0444205241
• Artikelnr.: 39028571

Inhaltsangabe

Selected Chapters. Perspectives of Blood Substitutes (E. Tsuchida). The
Role of Blood Substitutes in Emerging Healthcare Systems (R.M. Winslow).
Red Cell Substitutes: Evolution of Approaches for Demonstrating Efficacy
(J.C. Fratantoni). Recent Progress in the Development of Recombinant Human
Hemoglobin (rHb1.1) as an Oxygen Therapeutic (J.W. Freytag et al.). Update
on Perfluorocarbon-Based Oxygen Delivery Systems (J.G. Riess, P.E.
Keipert). Round Table Discussion: "The Target and Assessment of Clinical
Tests" (M. Takaori). Experimental and Mathematical Simulation of Oxygen
Transport by Hemoglobin-based Blood Substitute (T.C. Page et al.).
Polymeric Biodegradable Hemoglobin Nanocapsule as a New Red Blood Cell
Substitute (T.M.S. Chang). Microvascular Responses to Hemodilution with
Hb-Vesicles: Importance of Resistance Arteries and Mechanisms of
Vasoconstriction (H. Sakai et al.). In vivo Oxygenation of Deoxy-Hemolink
TM Following Exchange Transfusion of 50% or 90% the Blood Volume in Rats
(J. Ning et al.). The Heme Oxgenase System in Liver Microcirculation: A Key
Mechanism for Hemoglobin Degradation (M. Suematsu et al.). Zero-link
Polymerization: a New Class of Polymeric Hemoglobins (A. Razynska, E.
Bucci). Properties of Poly(ethylene glycol)-conjugated Red Blood Cells
(T.C. Fisher et al.). Fluorocarbon Emulsions as Blood Substitutes (K.C.
Lowe). Recent Developments and Future Perspectives for Preserved Platelets
and Platelet Substitutes (B.M. Alving, C, Krishnamurti). Impact on the
Appearance of Blood Substitutes Replacing Blood in Transfusion Medicine (S.
Sekiguchi).