Bone morphogenetic proteins (BMPs) are multi-functional growth factors that belong to the transforming growth factor beta (TGFbeta) superfamily and are responsible for migration, proliferation and differentiation of several cell types. They represent a unique set of differentiation factors that induce new bone formation at the site of implantation instead of changing the growth rate of pre-existing bone. BMPs have promising potential for clinical bone and cartilage repair, working as powerful bone-inducing components in diverse tissue-engineering products. Considering the expanding research, the field of regenerative medicine is expected to have brilliant prospects with the use of BMPs.This book reviews the current knowledge on BMP s and emphasis on their role as a potent stimulant in bone regeneration.