A field trial was conducted at Bangladesh Agricultural University (BAU) farm during 2010-2011 to evaluate the effect of foliar application of boron (B) on the grain set and yield of wheat (cv. Shatabdi). The experiment was designed with six boron treatments, arranged in a randomized complete block design (RCBD) with three replications.The B treatments were (i) B control, (ii) soil application of B, (iii) seed priming into boric acid solution, (iv) foliar spray of B at primordial stage of crop, (v) foliar spray of B at booting stage and (vi) foliar spray of B at primordial and booting stages. The rate of B for soil application was 1.5 kg B ha-1 from boric acid (17% B) and the rate for each foliar spray was 0.4% boric acid solution. Wheat yield was affected due to grain set failure induced by boron deficiency and it was possible to overcome this element deficiency by soil application at 1.5 kg B ha-1 or foliar application of 0.4% boric acid solution at primordial or booting stage of crop.