William M Pardridge

Brain Drug Targeting

The Future of Brain Drug Development

• Gebundenes Buch

Produktbeschreibung

This challenging 2001 book reviews modern neurotherapeutics from the point of view of drug targeting.

Produktdetails

• Verlag: Cambridge University Press
• Seitenzahl: 372
• Erscheinungstermin: 31. Mai 2001
• Englisch
• Abmessung: 250mm x 175mm x 25mm
• Gewicht: 829g
• ISBN-13: 9780521800778
• ISBN-10: 0521800773
• Artikelnr.: 22316939

Inhaltsangabe

Preface
1. Drug targeting, drug discovery, and brain drug development
2. Invasive drug delivery
3. Lipid-mediated transport and carrier-mediated transport of small molecules
4. Receptor-mediated transcytosis of peptides
5. Vector discovery: genetically-engineered trojan horses for drug targeting
6. Linker strategies: the engineering of multi-functional drug formulations
7. Protein neuropathies and peptide radiopharmaceuticals
8. Antisense neurotherapeutics and imaging gene expression in vivo
9. Gene therapy of the brain
10. Blood-brain barrier genomics
Epilogue
Bibliography.