Science writer Bijal P. Trivedi gives a comprehensive look at cystic fibrosis, from its late 1930s discovery to the recent development of breakthrough treatments for 90% of patients, and the way treatments for the previously fatal disease are opening the door for curing other life-threatening conditions.
Science writer Bijal P. Trivedi gives a comprehensive look at cystic fibrosis, from its late 1930s discovery to the recent development of breakthrough treatments for 90% of patients, and the way treatments for the previously fatal disease are opening the door for curing other life-threatening conditions.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Contents Introduction Part I Chapter 1: Hello, Joey 1974 Chapter 2: The Treatment Plan 1974 Chapter 3: Case 44: Babies Hospital, New York City 1935 Chapter 4: A New Disease 1936 1937 Chapter 5: An Equal Opportunity Disease 1938 1942 Chapter 6: Christmas Homecoming 1974 1977 Chapter 7: The Sweat Test 1943 1960 Chapter 8: A Tribe of Desperate Parents 1950 1955 Chapter 9: Lessons from Polio 1955 1960 Chapter 10: The Registry 1960 1966 Chapter 11: The Therapist 1977 Chapter 12: A Disease in Search of Ideas 1964 1980 Chapter 13: The Hitman Cometh 1979 1982 Chapter 14: Salt and Water 1970 1981 Chapter 15: Salty Boy 1981 1983 Chapter 16: Birth of an Advocate 1984 Chapter 17: Out of Many, One 1978 1984 Part 2 Chapter 18: The Gene Hunters 1980 1984 Chapter 19: Lucky Number Seven 1984 1985 Chapter 20: Kate 1986 Chapter 21: To Screen or Not to Screen Newborns 1985 Chapter 22: Michigan 1985 Chapter 23: Joey's Long Goodbye 1986 Chapter 24: Mad Pursuit 1987 Chapter 25: The Gene 1989 Chapter 26: Runny, Like Water 1989 1994 Chapter 27: Venture Philanthropy A New Way to Fund Drug Development 1977 1999 Chapter 28: The Gene Is the Medicine 1989 1991 Chapter 29: Transforming the Lungs 1992 2003 Chapter 30: First in Human Trials 1992 1993 Chapter 31: The Beall Curve 1996 Part 3 Chapter 32: The Joey Fund 1989 1999 Chapter 33: A Network for Developing Therapeutic Drugs 1997 1998 Chapter 34: Aurora 1998 1999 Chapter 35: The Gates Open 1987 2000 Chapter 36: A Tale of Four Families CF in the New Millennium 1999 Chapter 37: The Takeover 2001 Chapter 38: Getting the Band Together 2001 2003 Chapter 39: Pay to Play 2002 2004 Chapter 40: Molecular Architects of Vertex West 2004 2005 Chapter 41: Rat to Man 2003 2004 Chapter 42: A Christmas Gift 2004 2005 Chapter 43: The Lucky Four 2005 2007 Chapter 44: The Doorman Launches the Era of Genetic Medicine 2007 2008 Chapter 45: Disruption Fall 2008 Chapter 46: Tasting like Average People 2010 2012 Chapter 47: Milestones to a Cure 2004 2015 Chapter 48: Tackling the Common Mutation 2004 2013 Chapter 49: What Mutation Are You? 2013 2014 Chapter 50: The Mother of All Deals 2014 Chapter 51: Very Personal Clinical Trials 2021 2017 Chapter 52: The Triple 2015 2017 Chapter 53: The Home Stretch 2018 Chapter 54: The Leftovers 2015 2020 Chapter 55: A New Generation 2017 2020 Epilogue 2019 2020 Acknowledgments Timeline Endnotes About the Author
Contents Introduction Part I Chapter 1: Hello, Joey 1974 Chapter 2: The Treatment Plan 1974 Chapter 3: Case 44: Babies Hospital, New York City 1935 Chapter 4: A New Disease 1936 1937 Chapter 5: An Equal Opportunity Disease 1938 1942 Chapter 6: Christmas Homecoming 1974 1977 Chapter 7: The Sweat Test 1943 1960 Chapter 8: A Tribe of Desperate Parents 1950 1955 Chapter 9: Lessons from Polio 1955 1960 Chapter 10: The Registry 1960 1966 Chapter 11: The Therapist 1977 Chapter 12: A Disease in Search of Ideas 1964 1980 Chapter 13: The Hitman Cometh 1979 1982 Chapter 14: Salt and Water 1970 1981 Chapter 15: Salty Boy 1981 1983 Chapter 16: Birth of an Advocate 1984 Chapter 17: Out of Many, One 1978 1984 Part 2 Chapter 18: The Gene Hunters 1980 1984 Chapter 19: Lucky Number Seven 1984 1985 Chapter 20: Kate 1986 Chapter 21: To Screen or Not to Screen Newborns 1985 Chapter 22: Michigan 1985 Chapter 23: Joey's Long Goodbye 1986 Chapter 24: Mad Pursuit 1987 Chapter 25: The Gene 1989 Chapter 26: Runny, Like Water 1989 1994 Chapter 27: Venture Philanthropy A New Way to Fund Drug Development 1977 1999 Chapter 28: The Gene Is the Medicine 1989 1991 Chapter 29: Transforming the Lungs 1992 2003 Chapter 30: First in Human Trials 1992 1993 Chapter 31: The Beall Curve 1996 Part 3 Chapter 32: The Joey Fund 1989 1999 Chapter 33: A Network for Developing Therapeutic Drugs 1997 1998 Chapter 34: Aurora 1998 1999 Chapter 35: The Gates Open 1987 2000 Chapter 36: A Tale of Four Families CF in the New Millennium 1999 Chapter 37: The Takeover 2001 Chapter 38: Getting the Band Together 2001 2003 Chapter 39: Pay to Play 2002 2004 Chapter 40: Molecular Architects of Vertex West 2004 2005 Chapter 41: Rat to Man 2003 2004 Chapter 42: A Christmas Gift 2004 2005 Chapter 43: The Lucky Four 2005 2007 Chapter 44: The Doorman Launches the Era of Genetic Medicine 2007 2008 Chapter 45: Disruption Fall 2008 Chapter 46: Tasting like Average People 2010 2012 Chapter 47: Milestones to a Cure 2004 2015 Chapter 48: Tackling the Common Mutation 2004 2013 Chapter 49: What Mutation Are You? 2013 2014 Chapter 50: The Mother of All Deals 2014 Chapter 51: Very Personal Clinical Trials 2021 2017 Chapter 52: The Triple 2015 2017 Chapter 53: The Home Stretch 2018 Chapter 54: The Leftovers 2015 2020 Chapter 55: A New Generation 2017 2020 Epilogue 2019 2020 Acknowledgments Timeline Endnotes About the Author
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