Brucellosis is known by many different names such as Malta fever, Cyprus or Mediterranean fever, intermittent typhoid, Rock fever of Gibraltar, and more commonly, undulant fever is one of the most common contagious and communicable zoonotic diseases with high rates of morbidity and lifetime sterility. The disease brucellosis is distributed throughout the globe. Brucellosis is caused by Brucella species and usually transmits from animal to human through direct contact with the placenta, fetus, fetal fluids, and vaginal discharges or byproducts (e.g., milk, meat, and cheese) from infected animals. Professional health workers are frequent victims of Brucella infection, especially in regions of prevalent disease. Aerial bacteria also remain a severe threat have been observed in rare cases. Aerial bacteria also remain a severe threat of infection, either by inhaling organisms or through the conjunctiva. Brucellosis also spreads via vertical transmission, by infecting new-born calves and lambs in the uterus.