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This book introduces Markovian codon models of evolution in maximum likelihood phylogeny inference. The literature show that codon models constitute a more realistic representation of protein-coding sequences when compared against amino acid and nucleotide models. Our results extend this by showing that codon models are also expected to outperform these two competing approaches when re-constructing phylogenetic trees. To enable this analysis, we have created a software package called CodonPhyml, which is freely available under an open source license.

Produktbeschreibung
This book introduces Markovian codon models of evolution in maximum likelihood phylogeny inference. The literature show that codon models constitute a more realistic representation of protein-coding sequences when compared against amino acid and nucleotide models. Our results extend this by showing that codon models are also expected to outperform these two competing approaches when re-constructing phylogenetic trees. To enable this analysis, we have created a software package called CodonPhyml, which is freely available under an open source license.
Autorenporträt
Marcelo holds a Degree in Electrical Engineering from UNICAMP (Brazil), a Master in Computer Science from ETH ZÜRICH (Switzerland) and a Doctorate in Complex Systems and Software Engineering also from ETH ZÜRICH.