The general objective set out in this research was: to determine the relationship that exists between entrepreneurship and business model generation in a high school in the district of Ate Vitarte in the year 2019. The population and sample of the study comprised 93 students who are developing their business model. Significant relationship was detected between entrepreneurship and value proposition, significant relationship between entrepreneurship with revenue and costs of a business model, also significant relationship between entrepreneurship with activities, resources and key partners. Therefore, the Higher Institute must continue to strengthen the line of entrepreneurship, as it allows students from different careers to develop a series of skills to strengthen their entrepreneurial capacity. Strengthening this capacity will generate in them a competitive advantage over other students, and will also allow them to generate a business model (company) much more efficient and competitive in the market.