Stefan I. McDonough (Hrsg.)

Calcium Channel Pharmacology

Herausgeber: McDonough, Stefan I.

• Gebundenes Buch

Produktbeschreibung

This volume reviews the current ability, future prospects, and physiological and medical significance of being able to distinguish pharmacologically among different calcium channel subtypes. Chapters are organized around broad concepts addressing the state of the field that naturally cover the pharmacology of each different calcium channel. Mechanistic information on drug-channel interactions is also presented in several chapters, as a theoretical and practical guide to working with calcium channel blockers in general.

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Produktdetails

• Verlag: Springer, Berlin
• 2003
• Seitenzahl: 440
• Erscheinungstermin: 30. November 2003
• Englisch
• Abmessung: 260mm x 183mm x 32mm
• Gewicht: 1115g
• ISBN-13: 9780306478789
• ISBN-10: 0306478781
• Artikelnr.: 21654422

Inhaltsangabe

Introduction; S.I. McDonough. Concepts of State-Dependent Pharmacology of Calcium Channels; E.N. Timin, S. Berjukow, S. Hering. Pharmacology of Ca v 1 (L-Type) Channels; D.J. Triggle. The Therapeutic Utility of Targeting Ca v 2 Channels; C.J. Cohen, R.L. Kraus. Peptide Toxin Inhibition of Voltage Gated Calcium Channels: Selectivity and Mechanisms; S.I. McDonough. Calcium Channel Blocking Polypeptides: Structure, Function, and Molecular Mimicry; R.S. Norton, J.B. Baell, J.A. Angus. Pharmacology of Ca v 3 (T-Type) Channels; E.A. Ertel. Cellular Functions of Calcium Channel Subtypes; E.S. Piedras-Rentería, P.G. Mermelstein, G.S. Pitt. Genetic Approaches to the Elucidation of Calcium Channel Functions in Vivo; H. Saegusa, T. Tanabe. Calcium Channel Mutations and Associated Diseases; Y. Mori, Y. Itsukaichi, M. Nishida, H. Oka. Modulation of High Voltage-Activated Calcium Channels by G Protein-Coupled Receptors; A.M. Beedle, G.W. Zamponi. Alternative Splicing in Voltage Gated Calcium Channels; D. Lipscombe, A.J. Castiglioni. Index.