A practical guide to cancer genomics and its application to cancer diagnosis and care. Each chapter provides explanations of concepts, terminology, and methods. Also included are tips for interpreting and analysing molecular data, and discussion of molecular predictors for targeted therapies covering haematologic malignancies and solid tumours.
A practical guide to cancer genomics and its application to cancer diagnosis and care. Each chapter provides explanations of concepts, terminology, and methods. Also included are tips for interpreting and analysing molecular data, and discussion of molecular predictors for targeted therapies covering haematologic malignancies and solid tumours.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Contents Contributors Preface Acknowledgments 1. Genetic Alterations in Cancer Deepali Jain, Brett H. Herzog, and Leonard B. Maggi, Jr. 2. Tumor Mutational Profiling by Next-Generation Sequencing Samantha N. McNulty, Latisha Love-Gregory, and Jonathan W. Heusel 3. Bioinformatics: What a Clinician Should Know Irena Lanc and Arpad Danos 4. Tumor Heterogeneity Alex H. Wagner, Kilannin Krysiak, Katie M. Campbell, and Erica K. Barnell 5. Epigenetic Alterations in Cancer Erica C. Pehrsson, Hyo Sik Jang, and Ting Wang 6. Cell-Free DNA in Cancer Diagnosis and Follow Up Bruna Pellini Ferreira and Daniel Morgensztern 7. Optimizing Targeted Therapies Using Next-Generation Sequencing Brett H. Herzog and Saiama N. Waqar Index
Contents Contributors Preface Acknowledgments 1. Genetic Alterations in Cancer Deepali Jain, Brett H. Herzog, and Leonard B. Maggi, Jr. 2. Tumor Mutational Profiling by Next-Generation Sequencing Samantha N. McNulty, Latisha Love-Gregory, and Jonathan W. Heusel 3. Bioinformatics: What a Clinician Should Know Irena Lanc and Arpad Danos 4. Tumor Heterogeneity Alex H. Wagner, Kilannin Krysiak, Katie M. Campbell, and Erica K. Barnell 5. Epigenetic Alterations in Cancer Erica C. Pehrsson, Hyo Sik Jang, and Ting Wang 6. Cell-Free DNA in Cancer Diagnosis and Follow Up Bruna Pellini Ferreira and Daniel Morgensztern 7. Optimizing Targeted Therapies Using Next-Generation Sequencing Brett H. Herzog and Saiama N. Waqar Index
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